Term Information

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Accession
GO:0036134
Name
12-hydroxyheptadecatrienoic acid synthase activity
Ontology
molecular_function
Synonyms
prostaglandin H2 degradation activity
Alternate IDs
None
Definition
Catalysis of the reaction: prostaglandin H2 = 12-hydroxyheptadecatrienoic acid (HHT) + malonaldehyde (MDA). Source: PMID:11297515, GOC:mw
Comment
None
History
See term history for GO:0036134 at QuickGO
Chem. react.
has participant 12(S)-HHTrE(1-)
has participant prostaglandin H2(1-)
has participant malonaldehyde
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of 12-hydroxyheptadecatrienoic acid synthase activity (GO:0036134)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
12-hydroxyheptadecatrienoic acid synthase activity [RO:0000057 relation] RO:0000057  12(S)-HHTrE(1-) (CHEBI:90694)
12-hydroxyheptadecatrienoic acid synthase activity [RO:0000057 relation] RO:0000057  prostaglandin H2(1-) (CHEBI:57405)
12-hydroxyheptadecatrienoic acid synthase activity [RO:0000057 relation] RO:0000057  malonaldehyde (CHEBI:566274)
12-hydroxyheptadecatrienoic acid synthase activity [is_a relation] is_a  oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor (GO:0016628)

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Reactome
R-HSA-2161613
RHEA
48644