AmiGO 2: Term Details for "tyrosyl-RNA phosphodiesterase activity" (GO:0036317)

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Term Information

Accession: GO:0036317
Name: tyrosyl-RNA phosphodiesterase activity
Ontology: molecular_function
Synonyms: VPg unlinkase activity, Y-pUpN PDE activity, unlinkase activity, uridylylpolynucleotide-(5' P->O)- tyrosine phosphodiesterase activity
Alternate IDs: None
Definition: Catalysis of the hydrolysis of a 5' tyrosyl-RNA phosphodiester bond between a protein and RNA. In picornaviruses, this covalent bond connects VPg, a viral-encoded protein essential for RNA replication, to the 5' end of all nascent picornavirus genomes; it is cleaved from viral RNA prior to its engaging in protein synthesis. Source: GOC:sp, GOC:bf, PMID:22908287, PMID:21408223
Comment: None
History: See term history for GO:0036317 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to tyrosyl-RNA phosphodiesterase activity (excluding "regulates").; Link to all direct and indirect annotations to tyrosyl-RNA phosphodiesterase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for tyrosyl-RNA phosphodiesterase activity (excluding "regulates").

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GO:0003824 catalytic activity
GO:0016787 hydrolase activity
GO:0003674 molecular_function
GO:0016788 hydrolase activity, acting on ester bonds
GO:0140640 catalytic activity, acting on a nucleic acid
GO:0042578 phosphoric ester hydrolase activity
GO:0140098 catalytic activity, acting on RNA
GO:0008081 phosphoric diester hydrolase activity
GO:0036317 tyrosyl-RNA phosphodiesterase activity

Parents of tyrosyl-RNA phosphodiesterase activity (GO:0036317)

subject	relation	object
tyrosyl-RNA phosphodiesterase activity	is_a	phosphoric diester hydrolase activity (GO:0008081)
tyrosyl-RNA phosphodiesterase activity	is_a	catalytic activity, acting on RNA (GO:0140098)

This term has no children.