AmiGO 2: Term Details for "RNA N6-methyladenosine methyltransferase complex" (GO:0036396)

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Term Information

Accession: GO:0036396
Name: RNA N6-methyladenosine methyltransferase complex
Ontology: cellular_component
Synonyms: Mum2, Ime4, and Slz1 complex, WMM complex, METTL3-METTL14-WTAP methyltransferase complex, MIS complex, m(6)A writer complex, m6A methyltransferase complex
Alternate IDs: None
Definition: A RNA methyltransferase complex that catalyzes the post-transcriptional methylation of adenosine to form N6-methyladenosine (m6A). In budding yeast, the MIS complex consists of Mum2p, Ime4p and Slz1p. In vertebrates, the complex consists of METTL3, METTL14 and associated components WTAP, ZC3H13, VIRMA, CBLL1/HAKAI and in some cases of RBM15 (RBM15 or RBM15B). Source: PMID:29547716, GOC:sp, PMID:24407421, GOC:dgf, PMID:29507755, PMID:29535189, PMID:24316715, PMID:22685417
Comment: None
History: See term history for GO:0036396 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to RNA N6-methyladenosine methyltransferase complex (excluding "regulates").; Link to all direct and indirect annotations to RNA N6-methyladenosine methyltransferase complex (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for RNA N6-methyladenosine methyltransferase complex (excluding "regulates").

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CARO:0030000 biological entity
CARO:0000000 anatomical entity
UBERON:0001062 anatomical entity
CARO:0000006 material anatomical entity
GO:0003824 catalytic activity
GO:0005575 cellular_component
CARO:0000003 connected anatomical structure
UBERON:0000465 material anatomical entity
GO:0003674 molecular_function
PR:000050567 protein-containing material entity
UBERON:0000061 anatomical structure
GO:0140640 catalytic activity, acting on a nucleic acid
GO:0032991 protein-containing complex
GO:0016740 transferase activity
GO:0140098 catalytic activity, acting on RNA
GO:1902494 catalytic complex
CL:0000000 cell
GO:0110165 cellular anatomical entity
GO:0008168 methyltransferase activity
GO:0016741 transferase activity, transferring one-carbon groups
GO:0005622 intracellular anatomical structure
GO:0008173 RNA methyltransferase activity
GO:0008757 S-adenosylmethionine-dependent methyltransferase activity
GO:1990234 transferase complex
GO:0034708 methyltransferase complex
GO:0008174 mRNA methyltransferase activity
GO:0036396 RNA N6-methyladenosine methyltransferase complex

Parents of RNA N6-methyladenosine methyltransferase complex (GO:0036396)

subject	relation	object
RNA N6-methyladenosine methyltransferase complex	is_a	methyltransferase complex (GO:0034708)
RNA N6-methyladenosine methyltransferase complex	RO:0002215	mRNA methyltransferase activity (GO:0008174)

This term has no children.