Term Information

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Accession
GO:0036513
Name
Derlin-1 retrotranslocation complex
Ontology
cellular_component
Synonyms
Derlin-1 complex, Derlin-1 protein dislocation complex, Derlin-1 retro-translocation complex, Derlin-1 retrotranslocon, ERAD protein dislocation complex
Alternate IDs
None
Definition
A protein complex that functions in the retrotranslocation step of ERAD (ER-associated protein degradation), and includes at its core Derlin-1 oligomers forming a retrotranslocation channel. Source: GOC:PARL, PMID:16186510, GOC:bf, PMID:15215856
Comment
The Derlin-1 retrotranslocation complex is likely to assemble in steps, thereby containing different components at different stages of the retrotranslocation process.
History
See term history for GO:0036513 at QuickGO
Chem. react.
None
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of Derlin-1 retrotranslocation complex (GO:0036513)
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Derlin-1 retrotranslocation complex [is_a relation] is_a  membrane protein complex (GO:0098796)
Derlin-1 retrotranslocation complex [RO:0002216 relation] RO:0002216  retrograde protein transport, ER to cytosol (GO:0030970)
Derlin-1 retrotranslocation complex [BFO:0000050 relation] BFO:0000050  endoplasmic reticulum membrane (GO:0005789)
Derlin-1 retrotranslocation complex [is_a relation] is_a  endoplasmic reticulum protein-containing complex (GO:0140534)

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