AmiGO 2: Term Details for "large latent transforming growth factor-beta complex" (GO:0038045)

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Term Information

Accession: GO:0038045
Name: large latent transforming growth factor-beta complex
Ontology: cellular_component
Synonyms: LLC, large latent complex
Alternate IDs: None
Definition: A protein complex containing latency-associated proteins (LAPs), mature disulphide-linked dimeric TGF-beta, and latent TGF-beta binding proteins (LTBPs). TGF-beta is mostly secreted as part of the large latent complex, and must be subsequently released from the LLC in order to bind to cell surface receptors. Source: PMID:8680476, Reactome:R-HSA-177107, PMID:9805445, GOC:bf, PMID:2350783
Comment: None
History: See term history for GO:0038045 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to large latent transforming growth factor-beta complex (excluding "regulates").; Link to all direct and indirect annotations to large latent transforming growth factor-beta complex (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for large latent transforming growth factor-beta complex (excluding "regulates").

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GO:0005575 cellular_component
PR:000050567 protein-containing material entity
GO:0032991 protein-containing complex
GO:0038045 large latent transforming growth factor-beta complex

Parents of large latent transforming growth factor-beta complex (GO:0038045)

subject	relation	object
large latent transforming growth factor-beta complex	is_a	protein-containing complex (GO:0032991)

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