Term Information

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Accession
GO:0038060
Name
nitric oxide-cGMP-mediated signaling
Ontology
biological_process
Synonyms
NO-cGMP signaling pathway, canonical nitric oxide signaling, classical nitric oxide signaling, nitric oxide-cGMP-mediated signal transduction, nitric oxide-cGMP-mediated signaling pathway, nitric oxide-cGMP-mediated signalling pathway
Alternate IDs
None
Definition
An intracellular signaling cassette in which the signal is passed on within the cell by nitric oxide (NO) activating soluble guanylyl cyclase (sGC). Includes synthesis of nitric oxide, guanylyl cyclase activity, and downstream effectors that further transmit the signal within the cell following activation by cGMP. Source: GOC:signaling, PMID:21549190, PMID:22019632
Comment
None
History
See term history for GO:0038060 at QuickGO
Chem. react.
None
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of nitric oxide-cGMP-mediated signaling (GO:0038060)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
nitric oxide-cGMP-mediated signaling [is_a relation] is_a  cGMP-mediated signaling (GO:0019934)
nitric oxide-cGMP-mediated signaling [is_a relation] is_a  nitric oxide mediated signal transduction (GO:0007263)
Children of nitric oxide-cGMP-mediated signaling (GO:0038060)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
positive regulation of nitric oxide-cGMP mediated signal transduction (GO:0141150) [RO:0002213 relation] RO:0002213  nitric oxide-cGMP-mediated signaling
regulation of nitric oxide-cGMP mediated signal transduction (GO:0141149) [RO:0002211 relation] RO:0002211  nitric oxide-cGMP-mediated signaling
negative regulation of nitric oxide-cGMP mediated signal transduction (GO:0141151) [RO:0002212 relation] RO:0002212  nitric oxide-cGMP-mediated signaling
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