AmiGO 2: Term Details for "vascular endothelial growth factor signaling pathway" (GO:0038084)

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Term Information

Accession: GO:0038084
Name: vascular endothelial growth factor signaling pathway
Ontology: biological_process
Synonyms: VEGF signaling, VEGF-activated signaling pathway, vascular endothelial growth factor signalling pathway
Alternate IDs: None
Definition: The series of molecular signals initiated by vascular endothelial growth factor (VEGF) binding its receptor on the surface of the target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Source: GOC:signaling, PMID:17470632
Comment: In GO, a gene product with 'vascular endothelial growth factor-activated receptor activity ; GO:0005021' necessarily binds VEGF to transduce a signal. To represent cross-talk between ligands and receptors, signaling pathways in GO are starting to be named after the receptor and/or the signal. GO:0038084 is for annotation of any pathway in which the ligand VEGF binds and activates any cell surface receptor (VEGFR, PDGFR etc.). For annotation of signaling pathways where a VEGFR binds one of its physiological ligands (VEGF or an alternative growth factor), consider 'vascular endothelial growth factor receptor signaling pathway ; GO:0048010'.
History: See term history for GO:0038084 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to vascular endothelial growth factor signaling pathway (excluding "regulates").; Link to all direct and indirect annotations to vascular endothelial growth factor signaling pathway (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for vascular endothelial growth factor signaling pathway (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

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GO:0008150 biological_process
GO:0065007 biological regulation
GO:0009987 cellular process
GO:0050789 regulation of biological process
GO:0050896 response to stimulus
GO:0007154 cell communication
GO:0051716 cellular response to stimulus
GO:0050794 regulation of cellular process
GO:0023052 signaling
GO:0009719 response to endogenous stimulus
GO:0007165 signal transduction
GO:0007166 cell surface receptor signaling pathway
GO:0071495 cellular response to endogenous stimulus
GO:0070848 response to growth factor
GO:0071363 cellular response to growth factor stimulus
GO:0007167 enzyme-linked receptor protein signaling pathway
GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway
GO:0035924 cellular response to vascular endothelial growth factor stimulus
GO:0038084 vascular endothelial growth factor signaling pathway
GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway
GO:0038089 positive regulation of cell migration by vascular endothelial growth factor signaling pathway
GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway
GO:1900746 regulation of vascular endothelial growth factor signaling pathway
GO:0005021 vascular endothelial growth factor receptor activity
GO:0038190 VEGF-activated neuropilin signaling pathway
GO:0038086 VEGF-activated platelet-derived growth factor receptor signaling pathway

Parents of vascular endothelial growth factor signaling pathway (GO:0038084)

subject	relation	object
vascular endothelial growth factor signaling pathway	is_a	cell surface receptor protein tyrosine kinase signaling pathway (GO:0007169)
vascular endothelial growth factor signaling pathway	BFO:0000050	cellular response to vascular endothelial growth factor stimulus (GO:0035924)
vascular endothelial growth factor signaling pathway	RO:0002162	Vertebrata (NCBITaxon:7742)

Children of vascular endothelial growth factor signaling pathway (GO:0038084)

subject	relation	object
positive regulation of vascular endothelial growth factor signaling pathway (GO:1900748)	RO:0002213	vascular endothelial growth factor signaling pathway
negative regulation of vascular endothelial growth factor signaling pathway (GO:1900747)	RO:0002212	vascular endothelial growth factor signaling pathway
positive regulation of cell migration by vascular endothelial growth factor signaling pathway (GO:0038089)	is_a	vascular endothelial growth factor signaling pathway
vascular endothelial growth factor receptor activity (GO:0005021)	BFO:0000050	vascular endothelial growth factor signaling pathway
regulation of vascular endothelial growth factor signaling pathway (GO:1900746)	RO:0002211	vascular endothelial growth factor signaling pathway
VEGF-activated platelet-derived growth factor receptor signaling pathway (GO:0038086)	is_a	vascular endothelial growth factor signaling pathway
VEGF-activated neuropilin signaling pathway (GO:0038190)	is_a	vascular endothelial growth factor signaling pathway

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