Term Information

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Accession
GO:0039529
Name
RIG-I signaling pathway
Ontology
biological_process
Synonyms
DDX58 signaling pathway, RIG-I signalling pathway, RIG-I-like receptor (RLR) signaling pathway, RIG-like helicase signaling pathway, RIG-like receptor signaling pathway, RLH signaling pathway, RLR signaling pathway, retinoic acid inducible gene I signaling pathway
Alternate IDs
None
Definition
The series of molecular signals initiated by the binding ssRNA or dsRNA from another organism to the cytoplasmic pattern recognition receptor (PRR) RIG-1 (also known as DDX58). RIG-I detects RNA synthesized during viral replication or shed by non-viral pathogens, and triggers a signaling pathway to protect the host against infection, for example by inducing the expression of cytokines. Source: PMID:19620789, PMID:25579795, GOC:bf, PMID:17328678, PMID:21435580
Comment
None
History
See term history for GO:0039529 at QuickGO
Chem. react.
None
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Graph of GO:0039529 from QuickGO

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Parents of RIG-I signaling pathway (GO:0039529)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
RIG-I signaling pathway [is_a relation] is_a  cytoplasmic pattern recognition receptor signaling pathway (GO:0002753)
Children of RIG-I signaling pathway (GO:0039529)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
regulation of RIG-I signaling pathway (GO:0039535) [RO:0002211 relation] RO:0002211  RIG-I signaling pathway
negative regulation of RIG-I signaling pathway (GO:0039536) [RO:0002212 relation] RO:0002212  RIG-I signaling pathway
positive regulation of RIG-I signaling pathway (GO:1900246) [RO:0002213 relation] RO:0002213  RIG-I signaling pathway
None.