obsolete suppression by virus of host RIG-I K63-linked ubiquitination
Ontology
biological_process
Synonyms
inhibition by virus of TRIM25-mediated ubiquitination of host RIG-I, inhibition by virus of host DDX58 K63-linked ubiquitination, inhibition by virus of host RIG-I activity by inhibition of RIG-I ubiquitination
Alternate IDs
None
Definition
OBSOLETE. Any process in which a virus stops, prevents, or reduces the rate or extent of K63-linked ubiquitination of RIG-I (also known as DDX58), thereby suppressing RIG-I signal transduction. Lys63-linked ubiquitination of the N-terminal CARD domains of RIG-I is crucial for the cytosolic RIG-I signaling pathway to elicit host antiviral innate immunity.
Source:PMID:19454348,
PMID:21890623
Comment
The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately.
Link
to all genes and gene products annotated to obsolete suppression by virus of host RIG-I K63-linked ubiquitination (excluding "regulates").
Link
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to obsolete suppression by virus of host RIG-I K63-linked ubiquitination (excluding "regulates").
Link
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for obsolete suppression by virus of host RIG-I K63-linked ubiquitination (excluding "regulates").
