Term Information

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Accession
GO:0039554
Name
symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MDA-5 activity
Ontology
biological_process
Synonyms
Inhibition of host MDA5 by virus, inhibition by virus of host MDA-5 signaling, inhibition of host IFIH1/MDA5 by virus, suppression by virus of host IFIH1 signaling pathway, suppression by virus of host MDA-5 activity, suppression by virus of host MDA-5 signaling pathway, suppression by virus of host MDA-5 signalling pathway, suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity
Alternate IDs
GO:0039539
Definition
A process in which a symbiont interferes with, inhibits or disrupts a cytoplasmic pattern recognition receptor signaling pathway by inhibiting the activity of MDA-5 (also known as IFIH1). The cytoplasmic pattern recognition receptor MDA-5 detects dsRNA synthesized during active viral replication and triggers a signaling pathway to protect the host against viral infection, for example by inducing the expression of antiviral cytokines. Source: PMID:19019954, PMID:33727702
Comment
None
History
See term history for GO:0039554 at QuickGO
Chem. react.
None
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MDA-5 activity (GO:0039554)
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symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MDA-5 activity [is_a relation] is_a  symbiont-mediated suppression of cytoplasmic pattern recognition receptor signaling pathway (GO:0039537)

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VZ
603