obsolete suppression by virus of host STAT1 activity by tyrosine dephosphorylation of STAT1
Ontology
biological_process
Synonyms
suppression by virus of host STAT1 activity by peptidyl-tyrosine dephosphorylation of STAT1, viral tyrosine phosphatase activity involved in suppression of host STAT1
Alternate IDs
None
Definition
OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host STAT1 (signal transducer and activator of transcription-1) activity by the removal of phosphoric residues from STAT1-O-phospho-tyrosine to form STAT1-tyrosine. For example, the viral phosphatase VH1 dephosphorylates STAT1 to reverse STAT1 activation.
Source:PMID:11238845,
PMID:21362620,
VZ:282
Comment
The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately.
Link
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