symbiont-mediated suppression of host JAK-STAT cascade via inhibition of JAK1 activity
Ontology
biological_process
Synonyms
disruption by virus of host JAK-STAT cascade via inhibition of JAK1 activity, inhibition of host JAK activity by virus, negative regulation by virus of host JAK, negative regulation by virus of tyrosine phosphorylation of host STAT protein, suppression by virus of host JAK-STAT cascade via inhibition of JAK1 activity, suppression by virus of host JAK1 activity, suppression by virus of tyrosine phosphorylation of host STAT protein, viral inhibition of tyrosine phosphorylation of host STAT protein
Alternate IDs
GO:0039515
Definition
A process in which a symbiont interferes with, inhibits or disrupt a JAK-STAT signal cascade in the host organism by reducing the activity of host JAK1 (Janus Kinase 1).
Source:PMID:16188985
Comment
This term is for annotation of symbiont proteins that counteract the host innate immune response.
Link
to all genes and gene products annotated to symbiont-mediated suppression of host JAK-STAT cascade via inhibition of JAK1 activity (excluding "regulates").
Link
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to symbiont-mediated suppression of host JAK-STAT cascade via inhibition of JAK1 activity (excluding "regulates").
Link
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for symbiont-mediated suppression of host JAK-STAT cascade via inhibition of JAK1 activity (excluding "regulates").