AmiGO 2: Term Details for "symbiont-mediated suppression of host PKR/eIFalpha signaling" (GO:0039580)

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Term Information

Accession: GO:0039580
Name: symbiont-mediated suppression of host PKR/eIFalpha signaling
Ontology: biological_process
Synonyms: suppression by virus of host EIF2AK2 activity, suppression by virus of host PKR activity, suppression by virus of host PKR signaling
Alternate IDs: None
Definition: A process in which a symbiont inhibits or disrupts host PKR (Protein Kinase regulated by RNA) signaling. PKR phosphorylates host targets such as the translation initiation factor eIF2alpha that inhibits protein synthesis as an antimicrobial response. Inhibition of host PKR signaling maintains the host ability to translate mRNA. The host is defined as the larger of the organisms involved in a symbiotic interaction. Source: PMID:15207627
Comment: None
History: See term history for GO:0039580 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to symbiont-mediated suppression of host PKR/eIFalpha signaling (excluding "regulates").; Link to all direct and indirect annotations to symbiont-mediated suppression of host PKR/eIFalpha signaling (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for symbiont-mediated suppression of host PKR/eIFalpha signaling (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

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GO:0044419 biological process involved in interspecies interaction between organisms
GO:0008150 biological_process
GO:0044403 biological process involved in symbiotic interaction
GO:0051701 biological process involved in interaction with host
GO:0035821 modulation of process of another organism
GO:0009987 cellular process
GO:0044003 modulation by symbiont of host process
GO:0044068 symbiont-mediated perturbation of host cellular process
GO:0039656 symbiont-mediated perturbation of host gene expression
GO:0052027 symbiont-mediated perturbation of host signal transduction pathway
GO:0019057 symbiont-mediated perturbation of host translation
GO:0052029 symbiont-mediated suppression of host signal transduction pathway
GO:0141154 symbiont-mediated suppression of host-directed shutoff of host translation
GO:0039580 symbiont-mediated suppression of host PKR/eIFalpha signaling

Parents of symbiont-mediated suppression of host PKR/eIFalpha signaling (GO:0039580)

subject	relation	object
symbiont-mediated suppression of host PKR/eIFalpha signaling	is_a	symbiont-mediated suppression of host signal transduction pathway (GO:0052029)
symbiont-mediated suppression of host PKR/eIFalpha signaling	is_a	symbiont-mediated suppression of host-directed shutoff of host translation (GO:0141154)

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VZ: 554