AmiGO 2: Term Details for "sRNA-mediated post-transcriptional gene silencing" (GO:0040033)

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Term Information

Accession: GO:0040033
Name: sRNA-mediated post-transcriptional gene silencing
Ontology: biological_process
Synonyms: small RNA-mediated gene silencing, RNA-mediated gene silencing by inhibition of translation, downregulation of mRNA translation, ncRNA-mediated, inhibition of mRNA translation, ncRNA-mediated, sRNA-mediated gene silencing
Alternate IDs: None
Definition: A post-transcriptional gene silencing pathway mediated by the action of small regulatory non-coding RNAs (sRNAs). sRNAs are 20-500 nucleotides in length and found in bacteria. Source: PMID:2468565, PMID:33963446, PMID:12460531
Comment: It is postulated that there 3 mechanisms of sRNA-mediated gene silencing: (i) translation inhibition, (ii) RNA destabilization, and (iii) transcription termination loop formation (as this is common when looking at riboswitches). sRNA mediated gene silencing is sometimes referred to as 'regulation of riboswitch'.
History: See term history for GO:0040033 at QuickGO
Chem. react.: None
Subset: goslim_prokaryote
Related: Link to all genes and gene products annotated to sRNA-mediated post-transcriptional gene silencing (excluding "regulates").; Link to all direct and indirect annotations to sRNA-mediated post-transcriptional gene silencing (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for sRNA-mediated post-transcriptional gene silencing (excluding "regulates").

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For more information, please see the ontology relation documentation.

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GO:0008150 biological_process
GO:0065007 biological regulation
GO:0009987 cellular process
GO:0050789 regulation of biological process
GO:0009058 biosynthetic process
GO:0044237 cellular metabolic process
GO:0008152 metabolic process
GO:0048519 negative regulation of biological process
GO:0050794 regulation of cellular process
GO:0019222 regulation of metabolic process
GO:0044249 cellular biosynthetic process
GO:0043170 macromolecule metabolic process
GO:0048523 negative regulation of cellular process
GO:0009892 negative regulation of metabolic process
GO:0071704 organic substance metabolic process
GO:0009889 regulation of biosynthetic process
GO:0031323 regulation of cellular metabolic process
GO:0009059 macromolecule biosynthetic process
GO:0009890 negative regulation of biosynthetic process
GO:0031324 negative regulation of cellular metabolic process
GO:1901576 organic substance biosynthetic process
GO:0031326 regulation of cellular biosynthetic process
GO:0060255 regulation of macromolecule metabolic process
GO:0010467 gene expression
GO:0031327 negative regulation of cellular biosynthetic process
GO:0010605 negative regulation of macromolecule metabolic process
GO:0010556 regulation of macromolecule biosynthetic process
GO:0010558 negative regulation of macromolecule biosynthetic process
GO:0010468 regulation of gene expression
GO:0010629 negative regulation of gene expression
GO:0010608 post-transcriptional regulation of gene expression
GO:0016441 post-transcriptional gene silencing
GO:0031047 regulatory ncRNA-mediated gene silencing
GO:0035194 regulatory ncRNA-mediated post-transcriptional gene silencing
GO:0040033 sRNA-mediated post-transcriptional gene silencing

Parents of sRNA-mediated post-transcriptional gene silencing (GO:0040033)

subject	relation	object
sRNA-mediated post-transcriptional gene silencing	is_a	regulatory ncRNA-mediated post-transcriptional gene silencing (GO:0035194)
sRNA-mediated post-transcriptional gene silencing	RO:0002162	Bacteria (NCBITaxon:2)

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