AmiGO 2: Term Details for "error-prone translesion synthesis" (GO:0042276)

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Term Information

Accession: GO:0042276
Name: error-prone translesion synthesis
Ontology: biological_process
Synonyms: mutagenic PRR, error-prone postreplication DNA repair, mutagenic postreplication DNA repair
Alternate IDs: None
Definition: The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication by using a specialized DNA polymerase or replication complex to insert a defined nucleotide across the lesion. This process does not remove the replication-blocking lesions and causes an increase in the endogenous mutation level. For example, in E. coli, a low fidelity DNA polymerase, pol V, copies lesions that block replication fork progress. This produces mutations specifically targeted to DNA template damage sites, but it can also produce mutations at undamaged sites. Source: GOC:jl, GOC:elh, PMID:11485998
Comment: None
History: See term history for GO:0042276 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to error-prone translesion synthesis (excluding "regulates").; Link to all direct and indirect annotations to error-prone translesion synthesis (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for error-prone translesion synthesis (excluding "regulates").

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For more information, please see the ontology relation documentation.

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GO:0008150 biological_process
GO:0009987 cellular process
GO:0008152 metabolic process
GO:0071704 organic substance metabolic process
GO:0050896 response to stimulus
GO:0009058 biosynthetic process
GO:0044237 cellular metabolic process
GO:0051716 cellular response to stimulus
GO:0043170 macromolecule metabolic process
GO:0006139 nucleobase-containing compound metabolic process
GO:1901360 organic cyclic compound metabolic process
GO:1901576 organic substance biosynthetic process
GO:0044238 primary metabolic process
GO:0006950 response to stress
GO:0044249 cellular biosynthetic process
GO:0033554 cellular response to stress
GO:0090304 nucleic acid metabolic process
GO:1901362 organic cyclic compound biosynthetic process
GO:0006974 DNA damage response
GO:0006259 DNA metabolic process
GO:0009059 macromolecule biosynthetic process
GO:0141187 nucleic acid biosynthetic process
GO:0034654 nucleobase-containing compound biosynthetic process
GO:0071897 DNA biosynthetic process
GO:0006281 DNA repair
GO:0000731 DNA synthesis involved in DNA repair
GO:0006301 postreplication repair
GO:0019985 translesion synthesis
GO:0042276 error-prone translesion synthesis
GO:1904332 negative regulation of error-prone translesion synthesis
GO:1904333 positive regulation of error-prone translesion synthesis
GO:1904331 regulation of error-prone translesion synthesis

Parents of error-prone translesion synthesis (GO:0042276)

subject	relation	object
error-prone translesion synthesis	is_a	translesion synthesis (GO:0019985)

Children of error-prone translesion synthesis (GO:0042276)

subject	relation	object
positive regulation of error-prone translesion synthesis (GO:1904333)	RO:0002213	error-prone translesion synthesis
regulation of error-prone translesion synthesis (GO:1904331)	RO:0002211	error-prone translesion synthesis
negative regulation of error-prone translesion synthesis (GO:1904332)	RO:0002212	error-prone translesion synthesis

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