Term Information

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Accession
GO:0042284
Name
sphingolipid delta-4 desaturase activity
Ontology
molecular_function
Synonyms
delta-4 sphingolipid desaturase activity
Alternate IDs
None
Definition
Catalysis of the reaction: a dihydroceramide + 2 ferrocytochrome b5 + O2 + 2 H+ -> a sphingosine ceramide (aka (4E)-sphing-4-enine ceramide) + 2 ferricytochrome b5 + 2 H2O. Source: RHEA:46544, PMID:12417141
Comment
None
History
See term history for GO:0042284 at QuickGO
Chem. react.
has participant iron(3+)
has participant N-acylsphingosine
has participant iron(2+)
has participant hydron
has participant water
has participant N-acylsphinganine
has participant dioxygen
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Graph of GO:0042284 from QuickGO

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Parents of sphingolipid delta-4 desaturase activity (GO:0042284)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
sphingolipid delta-4 desaturase activity [RO:0000057 relation] RO:0000057  iron(3+) (CHEBI:29034)
sphingolipid delta-4 desaturase activity [RO:0000057 relation] RO:0000057  N-acylsphingosine (CHEBI:52639)
sphingolipid delta-4 desaturase activity [RO:0000057 relation] RO:0000057  iron(2+) (CHEBI:29033)
sphingolipid delta-4 desaturase activity [RO:0000057 relation] RO:0000057  hydron (CHEBI:15378)
sphingolipid delta-4 desaturase activity [RO:0000057 relation] RO:0000057  water (CHEBI:15377)
sphingolipid delta-4 desaturase activity [is_a relation] is_a  oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water (GO:0016717)
sphingolipid delta-4 desaturase activity [RO:0000057 relation] RO:0000057  N-acylsphinganine (CHEBI:31488)
sphingolipid delta-4 desaturase activity [RO:0000057 relation] RO:0000057  dioxygen (CHEBI:15379)

This term has no children.

EC
1.14.19.17
Reactome
R-HSA-428259
RHEA
46544