Term Information

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Accession
GO:0042289
Name
MHC class II protein binding
Ontology
molecular_function
Synonyms
major histocompatibility complex class II binding, major histocompatibility complex class II ligand
Alternate IDs
None
Definition
Binding to a major histocompatibility complex class II molecule; a set of molecules displayed on cell surfaces that are responsible for lymphocyte recognition and antigen presentation. Source: GOC:jl
Comment
Note that this term does not include binding to the antigen peptide bound to the MHC protein. Consider also annotating to the molecular function term 'peptide antigen binding ; GO:0042605' or one of its children.
History
See term history for GO:0042289 at QuickGO
Chem. react.
None
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Graph of GO:0042289 from QuickGO

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Parents of MHC class II protein binding (GO:0042289)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
MHC class II protein binding [is_a relation] is_a  MHC protein binding (GO:0042287)
Children of MHC class II protein binding (GO:0042289)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
MHC class II protein binding, via antigen binding groove (GO:0042658) [is_a relation] is_a  MHC class II protein binding
MHC class II receptor activity (GO:0032395) [BFO:0000051 relation] BFO:0000051  MHC class II protein binding
MHC class II protein binding, via lateral surface (GO:0042657) [is_a relation] is_a  MHC class II protein binding
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