AmiGO 2: Term Details for "replication fork arrest" (GO:0043111)

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Term Information

Accession: GO:0043111
Name: replication fork arrest
Ontology: biological_process
Synonyms: negative regulation of DNA replication at replication fork barrier, replication fork blocking, replication fork stalling
Alternate IDs: None
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of DNA replication by impeding the progress of the DNA replication fork. Replication fork arrest is one of the 'quality control' processes ensuring that DNA-dependent DNA replication occurs correctly. DNA replication fork arrest during DNA-dependent DNA replication is not known to occur outside of cases where a replication error needs to be prevented or corrected. Source: PMID:14645529, GOC:jl, GOC:pr
Comment: See also the biological process term 'site-specific replication termination ; GO:0071170' and its children.
History: See term history for GO:0043111 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to replication fork arrest (excluding "regulates").; Link to all direct and indirect annotations to replication fork arrest (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for replication fork arrest (excluding "regulates").

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For more information, please see the ontology relation documentation.

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GO:0008150 biological_process
GO:0065007 biological regulation
GO:0008152 metabolic process
GO:0044238 primary metabolic process
GO:0050789 regulation of biological process
GO:0019222 regulation of metabolic process
GO:0043170 macromolecule metabolic process
GO:0048519 negative regulation of biological process
GO:0006139 nucleobase-containing compound metabolic process
GO:0071704 organic substance metabolic process
GO:0080090 regulation of primary metabolic process
GO:0006259 DNA metabolic process
GO:0009892 negative regulation of metabolic process
GO:1901360 organic cyclic compound metabolic process
GO:0060255 regulation of macromolecule metabolic process
GO:0019219 regulation of nucleobase-containing compound metabolic process
GO:0006260 DNA replication
GO:0010605 negative regulation of macromolecule metabolic process
GO:0045934 negative regulation of nucleobase-containing compound metabolic process
GO:0051052 regulation of DNA metabolic process
GO:0006261 DNA-templated DNA replication
GO:0051053 negative regulation of DNA metabolic process
GO:0090304 nucleic acid metabolic process
GO:0006275 regulation of DNA replication
GO:0008156 negative regulation of DNA replication
GO:0090329 regulation of DNA-templated DNA replication
GO:0045005 DNA-templated DNA replication maintenance of fidelity
GO:2000104 negative regulation of DNA-templated DNA replication
GO:0043111 replication fork arrest
GO:0011000 replication fork arrest at mating type locus
GO:0031582 replication fork arrest at rDNA repeats
GO:0090001 replication fork arrest at tRNA locus
GO:0071807 replication fork arrest involved in DNA replication termination

Parents of replication fork arrest (GO:0043111)

subject	relation	object
replication fork arrest	is_a	DNA-templated DNA replication maintenance of fidelity (GO:0045005)
replication fork arrest	is_a	negative regulation of DNA-templated DNA replication (GO:2000104)

Children of replication fork arrest (GO:0043111)

subject	relation	object
replication fork arrest at tRNA locus (GO:0090001)	is_a	replication fork arrest
replication fork arrest at rDNA repeats (GO:0031582)	is_a	replication fork arrest
replication fork arrest at mating type locus (GO:0011000)	is_a	replication fork arrest
replication fork arrest involved in DNA replication termination (GO:0071807)	is_a	replication fork arrest

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