AmiGO 2: Term Details for "neurotrophin binding" (GO:0043121)

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Term Information

Accession: GO:0043121
Name: neurotrophin binding
Ontology: molecular_function
Synonyms: neurotrophic factor binding, neurotrophin TRK receptor activity, neurotrophin TRKA receptor activity, neurotrophin TRKB receptor activity, neurotrophin TRKC receptor activity, NT 4/5 binding, NT-3 binding, NT-4 binding, NT-4/5 binding, NT-5 binding, NT3 binding, NT4 binding, NT5 binding, neurotrophin 3 binding, neurotrophin 4/5 binding, neurotrophin-3 binding, neurotrophin-4/5 binding
Alternate IDs: GO:0048404, GO:0048405
Definition: Binding to a neurotrophin, any of a family of growth factors that prevent apoptosis in neurons and promote nerve growth. Source: GOC:jl
Comment: Note that mammalian NT-5 was initially named differently from amphibian NT-4 because of sequence differences, but the two genes were later shown to be functionally equivalent [SF:919858].
History: See term history for GO:0043121 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to neurotrophin binding (excluding "regulates").; Link to all direct and indirect annotations to neurotrophin binding (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for neurotrophin binding (excluding "regulates").

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For more information, please see the ontology relation documentation.

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GO:0003674 molecular_function
GO:0005488 binding
GO:0005515 protein binding
GO:0019838 growth factor binding
GO:0043121 neurotrophin binding
GO:0048403 brain-derived neurotrophic factor binding
GO:0048406 nerve growth factor binding

Parents of neurotrophin binding (GO:0043121)

subject	relation	object
neurotrophin binding	RO:0004009	neurotrophin-3 (PR:000011459)
neurotrophin binding	is_a	growth factor binding (GO:0019838)
neurotrophin binding	RO:0004009	neurotrophin (PR:000021998)

Children of neurotrophin binding (GO:0043121)

subject	relation	object
brain-derived neurotrophic factor binding (GO:0048403)	is_a	neurotrophin binding
nerve growth factor binding (GO:0048406)	is_a	neurotrophin binding
neurotrophin receptor activity (GO:0005030)	BFO:0000051	neurotrophin binding

neurotrophin binding