AmiGO 2: Term Details for "dendritic spine" (GO:0043197)

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Term Information

Accession: GO:0043197
Name: dendritic spine
Ontology: cellular_component
Synonyms: dendrite spine, branched dendritic spine, mushroom dendritic spine, sessile dendritic spine, stubby dendritic spine, thin dendritic spine
Alternate IDs: None
Definition: A small, membranous protrusion from a dendrite that forms a postsynaptic compartment, typically receiving input from a single presynapse. They function as partially isolated biochemical and an electrical compartments. Spine morphology is variable:they can be thin, stubby, mushroom, or branched, with a continuum of intermediate morphologies. They typically terminate in a bulb shape, linked to the dendritic shaft by a restriction. Spine remodeling is though to be involved in synaptic plasticity. Source: GOC:nln
Comment: None
History: See term history for GO:0043197 at QuickGO
Chem. react.: None
Subset: goslim_synapse
Related: Link to all genes and gene products annotated to dendritic spine (excluding "regulates").; Link to all direct and indirect annotations to dendritic spine (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for dendritic spine (excluding "regulates").

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For more information, please see the ontology relation documentation.

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UBERON:0000061 anatomical structure
GO:0008150 biological_process
UBERON:0010000 multicellular anatomical structure
CARO:0030000 biological entity
UBERON:0000468 multicellular organism
GO:0032501 multicellular organismal process
CARO:0000000 anatomical entity
UBERON:0000467 anatomical system
CL:0000000 cell
GO:0009987 cellular process
GO:0050877 nervous system process
GO:0003008 system process
UBERON:0001062 anatomical entity
GO:0007154 cell communication
GO:0110165 cellular anatomical structure
CL:0000211 electrically active cell
CL:0000255 eukaryotic cell
CARO:0000006 material anatomical entity
UBERON:0001016 nervous system
GO:0042995 cell projection
CARO:0000003 connected anatomical structure
CL:0000393 electrically responsive cell
CL:0000404 electrically signaling cell
UBERON:0000465 material anatomical entity
CL:0002319 neural cell
CL:0000540 neuron
GO:0019226 transmission of nerve impulse
GO:0030054 cell junction
GO:0005575 cellular_component
GO:0043005 neuron projection
GO:0120025 plasma membrane bounded cell projection
GO:0036477 somatodendritic compartment
GO:0097447 dendritic tree
GO:0045202 synapse
GO:0030425 dendrite
GO:0044309 neuron spine
GO:0098794 postsynapse
GO:0043197 dendritic spine
GO:0098836 cytoskeleton of dendritic spine
GO:0061846 dendritic spine cytoplasm
GO:0044327 dendritic spine head
GO:0032591 dendritic spine membrane
GO:0044326 dendritic spine neck
GO:0097444 spine apparatus
GO:0097464 thorny excrescence

Parents of dendritic spine (GO:0043197)

subject	relation	object
dendritic spine	BFO:0000050	dendrite (GO:0030425)
dendritic spine	is_a	neuron spine (GO:0044309)
dendritic spine	RO:0002162	Eumetazoa (NCBITaxon:6072)
dendritic spine	is_a	postsynapse (GO:0098794)

Children of dendritic spine (GO:0043197)

subject	relation	object
dendritic spine membrane (GO:0032591)	BFO:0000050	dendritic spine
dendritic spine cytoplasm (GO:0061846)	BFO:0000050	dendritic spine
dendritic spine neck (GO:0044326)	BFO:0000050	dendritic spine
dendritic spine head (GO:0044327)	BFO:0000050	dendritic spine
thorny excrescence (GO:0097464)	is_a	dendritic spine
cytoskeleton of dendritic spine (GO:0098836)	BFO:0000050	dendritic spine
dendritic spine organization (GO:0097061)	RO:0002592	dendritic spine
dendritic spine morphogenesis (GO:0060997)	RO:0002298	dendritic spine
spine apparatus (GO:0097444)	BFO:0000050	dendritic spine

NIF_Subcellular: sao1799103720
Wikipedia: Dendritic_spine