AmiGO 2: Term Details for "nuclear SCF ubiquitin ligase complex" (GO:0043224)

Accession: GO:0043224
Name: nuclear SCF ubiquitin ligase complex
Ontology: cellular_component
Synonyms: nuclear SCF complex, nuclear Skp1/Cul1/F-box protein complex, nuclear cullin complex
Alternate IDs: None
Definition: A ubiquitin ligase complex, located in the nucleus, in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1). Source: PMID:15688063, PMID:15571813
Comment: None
History: See term history for GO:0043224 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to nuclear SCF ubiquitin ligase complex (excluding "regulates").; Link to all direct and indirect annotations to nuclear SCF ubiquitin ligase complex (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for nuclear SCF ubiquitin ligase complex (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

subject	relation	object
nuclear SCF ubiquitin ligase complex	is_a	nuclear ubiquitin ligase complex (GO:0000152)
nuclear SCF ubiquitin ligase complex	is_a	SCF ubiquitin ligase complex (GO:0019005)
nuclear SCF ubiquitin ligase complex	BFO:0000050	nucleus (GO:0005634)

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