Term Information

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Accession
GO:0043409
Name
negative regulation of MAPK cascade
Ontology
biological_process
Synonyms
down regulation of MAPK cascade, down regulation of MAPKKK cascade, down-regulation of MAPK cascade, down-regulation of MAPKKK cascade, downregulation of MAPK cascade, downregulation of MAPKKK cascade, negative regulation of MAP kinase cascade, negative regulation of MAP kinase kinase kinase cascade, negative regulation of MAPKKK cascade, negative regulation of mitogen activated protein kinase cascade, negative regulation of mitogen activated protein kinase kinase kinase cascade, negative regulation of mitogen-activated protein kinase cascade, negative regulation of mitogen-activated protein kinase kinase kinase cascade, inhibition of MAPK cascade, inhibition of MAPKKK cascade
Alternate IDs
None
Definition
Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the MAPKKK cascade. Source: GOC:go_curators
Comment
None
History
See term history for GO:0043409 at QuickGO
Chem. react.
None
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of negative regulation of MAPK cascade (GO:0043409)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
negative regulation of MAPK cascade [is_a relation] is_a  regulation of MAPK cascade (GO:0043408)
negative regulation of MAPK cascade [RO:0002212 relation] RO:0002212  MAPK cascade (GO:0000165)
negative regulation of MAPK cascade [is_a relation] is_a  negative regulation of intracellular signal transduction (GO:1902532)
Children of negative regulation of MAPK cascade (GO:0043409)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
negative regulation of ERK1 and ERK2 cascade (GO:0070373) [is_a relation] is_a  negative regulation of MAPK cascade
negative regulation of p38MAPK cascade (GO:1903753) [is_a relation] is_a  negative regulation of MAPK cascade
negative regulation of MAP kinase activity (GO:0043407) [is_a relation] is_a  negative regulation of MAPK cascade
negative regulation of ERK5 cascade (GO:0070377) [is_a relation] is_a  negative regulation of MAPK cascade
negative regulation of JNK cascade (GO:0046329) [is_a relation] is_a  negative regulation of MAPK cascade
negative regulation of stress-activated MAPK cascade (GO:0032873) [is_a relation] is_a  negative regulation of MAPK cascade
negative regulation of pheromone response MAPK cascade (GO:0180040) [is_a relation] is_a  negative regulation of MAPK cascade
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