Term Information

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Accession
GO:0043490
Name
malate-aspartate shuttle
Ontology
biological_process
Synonyms
malate aspartate shuttle, malate/aspartate shuttle, malate:aspartate shuttle
Alternate IDs
None
Definition
The process of transferring reducing equivalents from the cytosol into the mitochondria; NADH is used to synthesise malate in the cytosol; this compound is then transported into the mitochondria where it is converted to oxaloacetate using NADH, the oxaloacetate reacts with gluamate to form aspartate, and the aspartate then returns to the cytosol to complete the cycle. Source: GOC:mtg_electron_transport, ISBN:0716743663, GOC:jl
Comment
None
History
See term history for GO:0043490 at QuickGO
Chem. react.
None
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of malate-aspartate shuttle (GO:0043490)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
malate-aspartate shuttle [BFO:0000050 relation] BFO:0000050  respiratory electron transport chain (GO:0022904)
malate-aspartate shuttle [is_a relation] is_a  mitochondrial transmembrane transport (GO:1990542)

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