Term Information

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Accession
GO:0043653
Name
mitochondrial fragmentation involved in apoptotic process
Ontology
biological_process
Synonyms
mitochondrial fission during apoptosis, mitochondrial fragmentation involved in apoptosis
Alternate IDs
None
Definition
The change in the morphology of the mitochondria in an apoptotic cell from a highly branched network to a fragmented vesicular form. Source: PMID:12867994, GOC:mtg_apoptosis, GOC:rk
Comment
Although most of the processes described under 'apoptotic mitochondrial changes' take place during the signaling phase of apoptosis, 'mitochondrial fragmentation involved in apoptotic process' cannot be confidently placed there. It is still controversial whether this process is involved in the signaling phase of apoptosis or not, so it was placed under the more generic 'apoptotic mitochondrial changes' parent rather than linked to the signaling or the execution phase until further research clarifies the matter.
History
See term history for GO:0043653 at QuickGO
Chem. react.
None
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of mitochondrial fragmentation involved in apoptotic process (GO:0043653)
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mitochondrial fragmentation involved in apoptotic process [is_a relation] is_a  apoptotic mitochondrial changes (GO:0008637)

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