AmiGO 2: Term Details for "cell dedifferentiation" (GO:0043697)

Accession: GO:0043697
Name: cell dedifferentiation
Ontology: biological_process
Synonyms: None
Alternate IDs: None
Definition: The process in which a specialized cell loses the structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these cells can revert back to the features of the stem cells that were their ancestors. Source: GOC:dph, GOC:pg
Comment: Note that this term should be used to annotate gene products involved in dedifferentiation that occurs as part of a normal process, such as regeneration. It should not be used for dedifferentiation that occurs in an abnormal or disease state such as cancer.
History: See term history for GO:0043697 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to cell dedifferentiation (excluding "regulates").; Link to all direct and indirect annotations to cell dedifferentiation (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for cell dedifferentiation (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

subject	relation	object
cell dedifferentiation	is_a	cellular developmental process (GO:0048869)
cell dedifferentiation	is_a	dedifferentiation (GO:0043696)

subject	relation	object
kidney cortex tubule cell dedifferentiation (GO:0160029)	is_a	cell dedifferentiation
cell dedifferentiation involved in phenotypic switching (GO:0090678)	is_a	cell dedifferentiation
hepatocyte dedifferentiation (GO:1990828)	is_a	cell dedifferentiation

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