AmiGO 2: Term Details for "acireductone synthase activity" (GO:0043874)

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Term Information

Accession: GO:0043874
Name: acireductone synthase activity
Ontology: molecular_function
Synonyms: 5-(methylthio)-2,3-dioxopentyl-phosphate phosphohydrolase (isomerizing), E-1, E-1 enolase-phosphatase
Alternate IDs: None
Definition: Catalysis of the reactions: 5-(methylthio)-2,3-dioxopentyl phosphate + H2O = 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate; (1a) 5-(methylthio)-2,3-dioxopentyl phosphate = 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate; (1b) 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate + H2O = 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate. Source: EC:3.1.3.77, RHEA:21700
Comment: This function is involved in the process of methionine salvage.
History: See term history for GO:0043874 at QuickGO
Chem. react.: has participant water; has participant 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one; has participant 5-(methylsulfanyl)-2,3-dioxopentyl phosphate(2-); has participant hydrogenphosphate
Subset: None
Related: Link to all genes and gene products annotated to acireductone synthase activity (excluding "regulates").; Link to all direct and indirect annotations to acireductone synthase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for acireductone synthase activity (excluding "regulates").

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GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016787 hydrolase activity
GO:0016788 hydrolase activity, acting on ester bonds
GO:0042578 phosphoric ester hydrolase activity
GO:0016791 phosphatase activity
GO:0043874 acireductone synthase activity

Parents of acireductone synthase activity (GO:0043874)

subject	relation	object
acireductone synthase activity	RO:0000057	water (CHEBI:15377)
acireductone synthase activity	RO:0000057	1,2-dihydroxy-5-(methylthio)pent-1-en-3-one (CHEBI:49252)
acireductone synthase activity	RO:0000057	5-(methylsulfanyl)-2,3-dioxopentyl phosphate(2-) (CHEBI:58828)
acireductone synthase activity	is_a	phosphatase activity (GO:0016791)
acireductone synthase activity	RO:0000057	hydrogenphosphate (CHEBI:43474)

This term has no children.

EC: 3.1.3.77
MetaCyc: 3.1.3.77-RXN
Reactome: R-HSA-1237129
RHEA: 21700