AmiGO 2: Term Details for "nuclear pore linkers" (GO:0044612)

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Term Information

Accession: GO:0044612
Name: nuclear pore linkers
Ontology: cellular_component
Synonyms: Nic96 complex, Nup82 complex
Alternate IDs: None
Definition: A substructure of the nuclear pore complex (NPC) that serves to connect members of the central transport channel (composed of FG-nucleoporins) to the core scaffold (composed of the inner and outer NPC rings). In S. cerevisiae, the linkers are Nic96p and Nup82p. In vertebrates, they are Nup93 and Nup88. Components are arranged in 8-fold symmetrical 'spokes' around the central transport channel. Both linkers can be isolated in association with specific FG-nucleoporins, complexes that are sometimes referred to as the Nic96 complex (Nic96p-Nsp1p-Nup49p-Nup57p) and the Nup82 complex (Nup82p-Nup116p-Nup159p-Gle2p). Source: PMID:18046406, GOC:dgf, PMID:19524430, PMID:20947011, PMID:22419078
Comment: None
History: See term history for GO:0044612 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to nuclear pore linkers (excluding "regulates").; Link to all direct and indirect annotations to nuclear pore linkers (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for nuclear pore linkers (excluding "regulates").

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CARO:0030000 biological entity
CARO:0000000 anatomical entity
UBERON:0001062 anatomical entity
CARO:0000006 material anatomical entity
CL:0000000 cell
GO:0110165 cellular anatomical entity
CARO:0000003 connected anatomical structure
UBERON:0000465 material anatomical entity
UBERON:0000061 anatomical structure
GO:0005575 cellular_component
GO:0005622 intracellular anatomical structure
GO:0043226 organelle
GO:0043229 intracellular organelle
GO:0043227 membrane-bounded organelle
GO:0012505 endomembrane system
GO:0043231 intracellular membrane-bounded organelle
GO:0005634 nucleus
GO:0031967 organelle envelope
PR:000050567 protein-containing material entity
GO:0005635 nuclear envelope
GO:0140513 nuclear protein-containing complex
GO:0032991 protein-containing complex
GO:0005643 nuclear pore
GO:0044612 nuclear pore linkers

Parents of nuclear pore linkers (GO:0044612)

subject	relation	object
nuclear pore linkers	BFO:0000050	nuclear pore (GO:0005643)
nuclear pore linkers	is_a	nuclear protein-containing complex (GO:0140513)

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