AmiGO 2: Term Details for "nuclear pore central transport channel" (GO:0044613)

Accession: GO:0044613
Name: nuclear pore central transport channel
Ontology: cellular_component
Synonyms: nuclear pore central channel, nuclear pore central plug, nuclear pore transport channel, karyopherin docking complex
Alternate IDs: None
Definition: The central substructure of the nuclear pore complex (NPC), through which nucleocytoplasmic transport of RNAs, proteins and small molecules occurs. The central transport channel is filled with FG-nucleoporins, which form a selective barrier and provide a series of binding sites for transporter proteins. Characterized S. cerevisiae FG-nucleoporins include Nup159p, Nup145Np, Nup116p, Nup100p, Nsp1p, Nup57p, Nup49p, Nup42p, Nup53p, Nup59p/Asm4p, Nup60p and Nup1. Characterized vertebrate FG-nucleoporins include Nup214, Nup98, Nup62, Nup54, Nup58/45, NLP1, and Nup153. Source: PMID:18046406, GOC:dgf, PMID:19524430, PMID:20947011, PMID:22419078
Comment: None
History: See term history for GO:0044613 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to nuclear pore central transport channel (excluding "regulates").; Link to all direct and indirect annotations to nuclear pore central transport channel (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for nuclear pore central transport channel (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

subject	relation	object
nuclear pore central transport channel	BFO:0000050	nuclear pore (GO:0005643)
nuclear pore central transport channel	is_a	nuclear protein-containing complex (GO:0140513)
nuclear pore central transport channel	RO:0002162	Eukaryota (NCBITaxon:2759)

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