AmiGO 2: Term Details for "retroviral integrase activity" (GO:0044823)

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Term Information

Accession: GO:0044823
Name: retroviral integrase activity
Ontology: molecular_function
Synonyms: None
Alternate IDs: None
Definition: Catalysis of the covalent insertion of double-stranded retroviral DNA into host DNA. Proceeds by an endonucleolytic cleavage at each 3'-OH extremity of the viral genome, named 3'-processing, followed by a strand transfer reaction leading to the insertion of the processed viral DNA into the target DNA by a trans-esterification mechanism. Source: PMID:19091057
Comment: None
History: See term history for GO:0044823 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to retroviral integrase activity (excluding "regulates").; Link to all direct and indirect annotations to retroviral integrase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for retroviral integrase activity (excluding "regulates").

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For more information, please see the ontology relation documentation.

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GO:0008150 biological_process
GO:0008152 metabolic process
GO:0071704 organic substance metabolic process
GO:1901360 organic cyclic compound metabolic process
GO:0044238 primary metabolic process
GO:0043170 macromolecule metabolic process
GO:0003674 molecular_function
GO:0006139 nucleobase-containing compound metabolic process
GO:0003824 catalytic activity
GO:0090304 nucleic acid metabolic process
GO:0140640 catalytic activity, acting on a nucleic acid
GO:0006259 DNA metabolic process
GO:0016032 viral process
GO:0140097 catalytic activity, acting on DNA
GO:0015074 DNA integration
GO:0019058 viral life cycle
GO:0008907 integrase activity
GO:0044826 viral genome integration into host DNA
GO:0044823 retroviral integrase activity
GO:0044824 retroviral 3' processing activity

Parents of retroviral integrase activity (GO:0044823)

subject	relation	object
retroviral integrase activity	BFO:0000050	viral genome integration into host DNA (GO:0044826)
retroviral integrase activity	is_a	integrase activity (GO:0008907)

Children of retroviral integrase activity (GO:0044823)

subject	relation	object
retroviral 3' processing activity (GO:0044824)	BFO:0000050	retroviral integrase activity

retroviral integrase activity