AmiGO 2: Term Details for "double-strand break repair via synthesis-dependent strand annealing" (GO:0045003)

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Term Information

Accession: GO:0045003
Name: double-strand break repair via synthesis-dependent strand annealing
Ontology: biological_process
Synonyms: mitotic gene conversion, SDSA
Alternate IDs: None
Definition: SDSA is a major mechanism of double-strand break repair in mitosis which allows for the error-free repair of a double-strand break without the exchange of adjacent sequences. The broken DNA searches for and base pairs with a homologous region in an intact chromosome. DNA synthesis initiates from the 3' end of the invading DNA strand, using the intact chromosome as the template. Newly synthesized DNA is then displaced from the template and anneal with its complement on the other side of the double-strand break. Source: PMID:10357855
Comment: None
History: See term history for GO:0045003 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to double-strand break repair via synthesis-dependent strand annealing (excluding "regulates").; Link to all direct and indirect annotations to double-strand break repair via synthesis-dependent strand annealing (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for double-strand break repair via synthesis-dependent strand annealing (excluding "regulates").

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GO:0008150 biological_process
GO:0008152 metabolic process
GO:0071704 organic substance metabolic process
GO:0009987 cellular process
GO:1901360 organic cyclic compound metabolic process
GO:0044238 primary metabolic process
GO:0050896 response to stimulus
GO:0051716 cellular response to stimulus
GO:0043170 macromolecule metabolic process
GO:0006139 nucleobase-containing compound metabolic process
GO:0006950 response to stress
GO:0033554 cellular response to stress
GO:0090304 nucleic acid metabolic process
GO:0006974 DNA damage response
GO:0006259 DNA metabolic process
GO:0006310 DNA recombination
GO:0006281 DNA repair
GO:0006302 double-strand break repair
GO:0000725 recombinational repair
GO:0000724 double-strand break repair via homologous recombination
GO:0045003 double-strand break repair via synthesis-dependent strand annealing
GO:0010791 DNA double-strand break processing involved in repair via synthesis-dependent strand annealing
GO:0000730 DNA recombinase assembly
GO:0010709 heteroduplex formation involved in double-strand break repair via synthesis-dependent strand annealing
GO:1902346 meiotic strand displacement involved in double-strand break repair via SDSA

Parents of double-strand break repair via synthesis-dependent strand annealing (GO:0045003)

subject	relation	object
double-strand break repair via synthesis-dependent strand annealing	is_a	double-strand break repair via homologous recombination (GO:0000724)

Children of double-strand break repair via synthesis-dependent strand annealing (GO:0045003)

subject	relation	object
meiotic strand displacement involved in double-strand break repair via SDSA (GO:1902346)	BFO:0000050	double-strand break repair via synthesis-dependent strand annealing
DNA double-strand break processing involved in repair via synthesis-dependent strand annealing (GO:0010791)	BFO:0000050	double-strand break repair via synthesis-dependent strand annealing
DNA recombinase assembly (GO:0000730)	BFO:0000050	double-strand break repair via synthesis-dependent strand annealing
heteroduplex formation involved in double-strand break repair via synthesis-dependent strand annealing (GO:0010709)	BFO:0000050	double-strand break repair via synthesis-dependent strand annealing

double-strand break repair via synthesis-dependent strand annealing