AmiGO 2: Term Details for "lipopolysaccharide receptor complex" (GO:0046696)

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Term Information

Accession: GO:0046696
Name: lipopolysaccharide receptor complex
Ontology: cellular_component
Synonyms: LPS receptor complex
Alternate IDs: None
Definition: A multiprotein complex that consists of at least three proteins, CD14, TLR4, and MD-2, each of which is glycosylated and which functions as a lipopolysaccharide (LPS) receptor that primes the innate immune response against bacterial pathogens. Source: PMID:9665271, PMID:11706042
Comment: Note that this term should not be used to refer to CD14 alone, but the multiprotein receptor complex that it is part of.
History: See term history for GO:0046696 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to lipopolysaccharide receptor complex (excluding "regulates").; Link to all direct and indirect annotations to lipopolysaccharide receptor complex (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for lipopolysaccharide receptor complex (excluding "regulates").

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For more information, please see the ontology relation documentation.

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GO:0008150 biological_process
CARO:0030000 biological entity
GO:0044419 biological process involved in interspecies interaction between organisms
GO:0043207 response to external biotic stimulus
GO:0050896 response to stimulus
CARO:0000000 anatomical entity
GO:0065007 biological regulation
GO:0009607 response to biotic stimulus
GO:0009605 response to external stimulus
GO:0051707 response to other organism
UBERON:0001062 anatomical entity
GO:0009987 cellular process
GO:0051716 cellular response to stimulus
CARO:0000006 material anatomical entity
GO:0050789 regulation of biological process
GO:0009617 response to bacterium
GO:0042221 response to chemical
GO:0007154 cell communication
GO:0071216 cellular response to biotic stimulus
GO:0070887 cellular response to chemical stimulus
CARO:0000003 connected anatomical structure
UBERON:0000465 material anatomical entity
GO:0050794 regulation of cellular process
GO:0033993 response to lipid
GO:0002237 response to molecule of bacterial origin
GO:1901700 response to oxygen-containing compound
GO:0023052 signaling
UBERON:0000061 anatomical structure
GO:0071396 cellular response to lipid
GO:0071219 cellular response to molecule of bacterial origin
GO:1901701 cellular response to oxygen-containing compound
GO:0005575 cellular_component
GO:0003674 molecular_function
GO:0032496 response to lipopolysaccharide
GO:0007165 signal transduction
GO:0007166 cell surface receptor signaling pathway
GO:0110165 cellular anatomical structure
GO:0071222 cellular response to lipopolysaccharide
GO:0060089 molecular transducer activity
GO:0038023 signaling receptor activity
GO:0031663 lipopolysaccharide-mediated signaling pathway
GO:0016020 membrane
GO:0038187 pattern recognition receptor activity
GO:0032991 protein-containing complex
GO:0001875 lipopolysaccharide immune receptor activity
GO:0098796 membrane protein complex
GO:0043235 receptor complex
GO:0046696 lipopolysaccharide receptor complex

Parents of lipopolysaccharide receptor complex (GO:0046696)

subject	relation	object
lipopolysaccharide receptor complex	is_a	membrane protein complex (GO:0098796)
lipopolysaccharide receptor complex	RO:0002215	lipopolysaccharide immune receptor activity (GO:0001875)
lipopolysaccharide receptor complex	is_a	receptor complex (GO:0043235)

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