Term Information

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Accession
GO:0047015
Name
3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity
Ontology
molecular_function
Synonyms
(2S,3S)-3-hydroxy-2-methylbutanoyl-CoA:NAD+ oxidoreductase activity, 2-methyl-3-hydroxy-butyryl CoA dehydrogenase activity, 2-methyl-3-hydroxybutyryl coenzyme A dehydrogenase activity, 2-methyl-3-hydroxybutyryl-CoA dehydrogenase activity
Alternate IDs
None
Definition
Catalysis of the reaction: NAD+ + 2-methyl-3-hydroxybutyryl-CoA = NADH + H+ + 2-methylaceto-acetyl-CoA. Source: EC:1.1.1.178, MetaCyc:1.1.1.178-RXN
Comment
None
History
See term history for GO:0047015 at QuickGO
Chem. react.
has participant hydron
has participant NADH(2-)
has participant (2S,3S)-3-hydroxy-2-methylbutanoyl-CoA(4-)
has participant NAD(1-)
has participant 2-methylacetoacetyl-CoA(4-)
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Graph of GO:0047015 from QuickGO

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Parents of 3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity (GO:0047015)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity [RO:0000057 relation] RO:0000057  hydron (CHEBI:15378)
3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity [is_a relation] is_a  oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616)
3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity [RO:0000057 relation] RO:0000057  NADH(2-) (CHEBI:57945)
3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity [RO:0000057 relation] RO:0000057  (2S,3S)-3-hydroxy-2-methylbutanoyl-CoA(4-) (CHEBI:57312)
3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity [RO:0000057 relation] RO:0000057  NAD(1-) (CHEBI:57540)
3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity [RO:0000057 relation] RO:0000057  2-methylacetoacetyl-CoA(4-) (CHEBI:57335)

This term has no children.

EC
1.1.1.178
MetaCyc
1.1.1.178-RXN
RHEA
13281