AmiGO 2: Term Details for "prostaglandin-F synthase activity" (GO:0047017)

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Term Information

Accession: GO:0047017
Name: prostaglandin-F synthase activity
Ontology: molecular_function
Synonyms: (5Z,13E)-(15S)-9alpha,11alpha,15-trihydroxyprosta-5,13-dienoate:NADP+ 11-oxidoreductase activity, NADPH-dependent prostaglandin D2 11-keto reductase activity, PGD(2) 11-ketoreductase activity, PGD2 11-ketoreductase activity, PGF synthetase activity, PGF2alpha synthetase activity, prostaglandin 11-keto reductase activity, prostaglandin 11-ketoreductase activity, prostaglandin D2-ketoreductase activity, prostaglandin F synthase activity, prostaglandin F synthetase activity, prostaglandin-D(2) 11-ketoreductase activity, prostaglandin-D(2) 11-reductase activity, prostaglandin-D(2) ketoreductase activity, prostaglandin-D2 11-ketoreductase activity, prostaglandin-D2 11-reductase activity, prostaglandin-D2 ketoreductase activity, prostaglandin-F synthetase activity, reductase, 15-hydroxy-11-oxoprostaglandin, synthetase, prostaglandin F2alpha
Alternate IDs: None
Definition: Catalysis of the reaction: NADP+ + (5Z,13E)-(15S)-9-alpha,11-alpha,15-trihydroxyprosta-5,13-dienoate = NADPH + H+ + (5Z,13E)-(15S)-9-alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate. Source: EC:1.1.1.188, MetaCyc:1.1.1.188-RXN
Comment: None
History: See term history for GO:0047017 at QuickGO
Chem. react.: has participant NADPH(4-); has participant prostaglandin D2(1-); has participant NADP(3-); has participant hydron; has participant prostaglandin F2alpha(1-)
Subset: None
Related: Link to all genes and gene products annotated to prostaglandin-F synthase activity (excluding "regulates").; Link to all direct and indirect annotations to prostaglandin-F synthase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for prostaglandin-F synthase activity (excluding "regulates").

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For more information, please see the ontology relation documentation.

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GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016491 oxidoreductase activity
GO:0016614 oxidoreductase activity, acting on CH-OH group of donors
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0047017 prostaglandin-F synthase activity

Parents of prostaglandin-F synthase activity (GO:0047017)

subject	relation	object
prostaglandin-F synthase activity	RO:0000057	NADPH(4-) (CHEBI:57783)
prostaglandin-F synthase activity	is_a	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616)
prostaglandin-F synthase activity	RO:0000057	prostaglandin D2(1-) (CHEBI:57406)
prostaglandin-F synthase activity	RO:0000057	NADP(3-) (CHEBI:58349)
prostaglandin-F synthase activity	RO:0000057	hydron (CHEBI:15378)
prostaglandin-F synthase activity	RO:0000057	prostaglandin F2alpha(1-) (CHEBI:57404)

This term has no children.

EC: 1.1.1.188
MetaCyc: 1.1.1.188-RXN
RHEA: 10140