AmiGO 2: Term Details for "15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity" (GO:0047020)

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Term Information

Accession: GO:0047020
Name: 15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity
Ontology: molecular_function
Synonyms: (5Z,13E)-(15S)-9alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate:NADP+ 15-oxidoreductase activity, 15-hydroxy PGD2 dehydrogenase activity, 15-hydroxyprostaglandin dehydrogenase (NADP), NADP-PGD2 dehydrogenase activity, NADP-linked prostaglandin D2 dehydrogenase activity, dehydrogenase, 15-hydroxyprostaglandin (nicotinamide adenine dinucleotide phosphate), dehydrogenase, prostaglandin D2, prostaglandin D2 dehydrogenase activity, prostaglandin-D 15-dehydrogenase (NADP(+)) activity, prostaglandin-D 15-dehydrogenase (NADP), prostaglandin-D 15-dehydrogenase (NADP+) activity, NADP-dependent 15-hydroxyprostaglandin dehydrogenase, NADP-linked 15-hydroxyprostaglandin dehydrogenase, NADP-specific 15-hydroxyprostaglandin dehydrogenase
Alternate IDs: None
Definition: Catalysis of the reaction: NADP+ + (5Z,13E)-(15S)-9-alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate = NADPH + H+ + (5Z,13E)-9-alpha-hydroxy-11,15-dioxoprosta-5,13-dienoate. Source: EC:1.1.1.196, MetaCyc:1.1.1.196-RXN
Comment: None
History: See term history for GO:0047020 at QuickGO
Chem. react.: has participant NADPH(4-); has participant NADP(3-); has participant 15-dehydro-prostaglandin D2(1-); has participant hydron; has participant prostaglandin D2(1-)
Subset: None
Related: Link to all genes and gene products annotated to 15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity (excluding "regulates").; Link to all direct and indirect annotations to 15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for 15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity (excluding "regulates").

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For more information, please see the ontology relation documentation.

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GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016491 oxidoreductase activity
GO:0016614 oxidoreductase activity, acting on CH-OH group of donors
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0047020 15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity

Parents of 15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity (GO:0047020)

subject	relation	object
15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity	RO:0000057	NADPH(4-) (CHEBI:57783)
15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity	RO:0000057	NADP(3-) (CHEBI:58349)
15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity	is_a	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616)
15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity	RO:0000057	15-dehydro-prostaglandin D2(1-) (CHEBI:57408)
15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity	RO:0000057	hydron (CHEBI:15378)
15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity	RO:0000057	prostaglandin D2(1-) (CHEBI:57406)

This term has no children.

EC: 1.1.1.196
MetaCyc: 1.1.1.196-RXN
RHEA: 20744