Term Information

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Accession
GO:0047024
Name
5alpha-androstane-3beta,17beta-diol dehydrogenase activity
Ontology
molecular_function
Synonyms
3-beta-HSD activity, progesterone reductase activity, 3-beta(or 20-alpha)-hydroxysteroid dehydrogenase activity, 3beta(or 20alpha)-hydroxysteroid dehydrogenase activity, 3beta(or 20alpha)-hydroxysteroid:NADP+ oxidoreductase activity, 3beta,20alpha-hydroxysteroid oxidoreductase activity, dehydrogenase, 3beta,20alpha-hydroxy steroid
Alternate IDs
None
Definition
Catalysis of the reaction: 5alpha-androstane-3beta,17beta-diol + NADP+ = 17beta-hydroxy-5alpha-androstan-3-one + H+ + NADPH. Source: EC:1.1.1.210, RHEA:16297
Comment
None
History
See term history for GO:0047024 at QuickGO
Chem. react.
has participant 17beta-hydroxy-5alpha-androstan-3-one
has participant NADPH(4-)
has participant hydron
has participant 5alpha-androstane-3beta,17beta-diol
has participant NADP(3-)
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of 5alpha-androstane-3beta,17beta-diol dehydrogenase activity (GO:0047024)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
5alpha-androstane-3beta,17beta-diol dehydrogenase activity [RO:0000057 relation] RO:0000057  17beta-hydroxy-5alpha-androstan-3-one (CHEBI:16330)
5alpha-androstane-3beta,17beta-diol dehydrogenase activity [is_a relation] is_a  steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0033764)
5alpha-androstane-3beta,17beta-diol dehydrogenase activity [RO:0000057 relation] RO:0000057  NADPH(4-) (CHEBI:57783)
5alpha-androstane-3beta,17beta-diol dehydrogenase activity [RO:0000057 relation] RO:0000057  hydron (CHEBI:15378)
5alpha-androstane-3beta,17beta-diol dehydrogenase activity [RO:0000057 relation] RO:0000057  5alpha-androstane-3beta,17beta-diol (CHEBI:18329)
5alpha-androstane-3beta,17beta-diol dehydrogenase activity [RO:0000057 relation] RO:0000057  NADP(3-) (CHEBI:58349)

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EC
1.1.1.210
KEGG_REACTION
R04344
MetaCyc
1.1.1.210-RXN
RHEA
16297