AmiGO 2: Term Details for "saccharopine dehydrogenase (NADP+, L-lysine-forming) activity" (GO:0047130)

Term Information

Accession: GO:0047130
Name: saccharopine dehydrogenase (NADP+, L-lysine-forming) activity
Ontology: molecular_function
Synonyms: 6-N-(L-1,3-dicarboxypropyl)-L-lysine:NADP+ oxidoreductase (L-lysine-forming), L-lysine-alpha-ketoglutarate reductase activity, N6-(L-1,3-dicarboxypropyl)-L-lysine:NADP+ oxidoreductase (L-lysine-forming), lysine:alpha-ketoglutarate:TPNH oxidoreductase (epsilon-N-[gultaryl-2]-L-lysine forming), saccharopine (nicotinamide adenine dinucleotide phosphate, lysine-forming) dehydrogenase activity
Alternate IDs: GO:0010010
Definition: Catalysis of the reaction: L-saccharopine + H2O + NADP+ = 2-oxoglutarate + L-lysine + H+ + NADPH. Source: RHEA:19373, EC:1.5.1.8
Comment: None
History: See term history for GO:0047130 at QuickGO
Chem. react.: has participant hydron; has participant L-lysinium(1+); has participant L-saccharopinate(1-); has participant NADP(3-); has participant 2-oxoglutarate(2-); has participant water; has participant NADPH(4-)
Subset: None
Related: Link to all genes and gene products annotated to saccharopine dehydrogenase (NADP+, L-lysine-forming) activity (excluding "regulates").; Link to all direct and indirect annotations to saccharopine dehydrogenase (NADP+, L-lysine-forming) activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for saccharopine dehydrogenase (NADP+, L-lysine-forming) activity (excluding "regulates").

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For more information, please see the ontology relation documentation.

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OLSVis (interactive)

Additional internal viewing options

GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016491 oxidoreductase activity
GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors
GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
GO:0004753 saccharopine dehydrogenase activity
GO:0047130 saccharopine dehydrogenase (NADP+, L-lysine-forming) activity

Parents of saccharopine dehydrogenase (NADP+, L-lysine-forming) activity (GO:0047130)

subject	relation	object
saccharopine dehydrogenase (NADP+, L-lysine-forming) activity	RO:0000057	hydron (CHEBI:15378)
saccharopine dehydrogenase (NADP+, L-lysine-forming) activity	RO:0000057	L-lysinium(1+) (CHEBI:32551)
saccharopine dehydrogenase (NADP+, L-lysine-forming) activity	RO:0000057	L-saccharopinate(1-) (CHEBI:57951)
saccharopine dehydrogenase (NADP+, L-lysine-forming) activity	RO:0000057	NADP(3-) (CHEBI:58349)
saccharopine dehydrogenase (NADP+, L-lysine-forming) activity	RO:0000057	2-oxoglutarate(2-) (CHEBI:16810)
saccharopine dehydrogenase (NADP+, L-lysine-forming) activity	RO:0000057	water (CHEBI:15377)
saccharopine dehydrogenase (NADP+, L-lysine-forming) activity	RO:0000057	NADPH(4-) (CHEBI:57783)
saccharopine dehydrogenase (NADP+, L-lysine-forming) activity	is_a	saccharopine dehydrogenase activity (GO:0004753)

This term has no children.

EC: 1.5.1.8
KEGG_REACTION: R00716
MetaCyc: 1.5.1.8-RXN
Reactome: R-HSA-70938
RHEA: 19373