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Accession
GO:0047442
Name
17-alpha-hydroxyprogesterone aldolase activity
Ontology
molecular_function
Synonyms
17-alpha-hydroxyprogesterone acetaldehyde-lyase activity, 17alpha-hydroxyprogesterone acetaldehyde-lyase (4-androstene-3,17-dione-forming), 17alpha-hydroxyprogesterone acetaldehyde-lyase activity, 17alpha-hydroxyprogesterone aldolase activity, C-17/C-20 lyase activity
Alternate IDs
None
Definition
Catalysis of the reaction: 17alpha-hydroxyprogesterone + O2 + reduced NADPH--hemoprotein reductase = acetate + androst-4-ene-3,17-dione + 2 H+ + H2O + oxidized NADPH--hemoprotein reductase. Source: RHEA:14753, MetaCyc:4.1.2.30-RXN
Comment
None
History
See term history for GO:0047442 at QuickGO
Chem. react.
has participant FMN(3-)
has participant androst-4-ene-3,17-dione
has participant 17alpha-hydroxyprogesterone
has participant dioxygen
has participant acetate
has participant hydron
has participant FMNH2(2-)
has participant water
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of 17-alpha-hydroxyprogesterone aldolase activity (GO:0047442)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
17-alpha-hydroxyprogesterone aldolase activity [RO:0000057 relation] RO:0000057  FMN(3-) (CHEBI:58210)
17-alpha-hydroxyprogesterone aldolase activity [RO:0000057 relation] RO:0000057  androst-4-ene-3,17-dione (CHEBI:16422)
17-alpha-hydroxyprogesterone aldolase activity [RO:0000057 relation] RO:0000057  17alpha-hydroxyprogesterone (CHEBI:17252)
17-alpha-hydroxyprogesterone aldolase activity [is_a relation] is_a  oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705)
17-alpha-hydroxyprogesterone aldolase activity [RO:0000057 relation] RO:0000057  dioxygen (CHEBI:15379)
17-alpha-hydroxyprogesterone aldolase activity [RO:0000057 relation] RO:0000057  acetate (CHEBI:30089)
17-alpha-hydroxyprogesterone aldolase activity [RO:0000057 relation] RO:0000057  hydron (CHEBI:15378)
17-alpha-hydroxyprogesterone aldolase activity [RO:0000057 relation] RO:0000057  FMNH2(2-) (CHEBI:57618)
17-alpha-hydroxyprogesterone aldolase activity [RO:0000057 relation] RO:0000057  water (CHEBI:15377)

This term has no children.

EC
1.14.14.32
MetaCyc
4.1.2.30-RXN
RHEA
14753