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UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase activity

Term Information

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Accession
GO:0047482
Name
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase activity
Ontology
molecular_function
Synonyms
L-lysine-adding enzyme activity, MurE synthetase activity, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:L-lysine gamma-ligase (ADP-forming), UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine synthetase activity, UPD-MurNAc-L-Ala-D-Glu:L-Lys ligase activity, uridine diphospho-N-acetylmuramoylalanyl-D-glutamyllysine synthetase activity
Alternate IDs
None
Definition
Catalysis of the reaction: L-lysine + ATP + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate = ADP + 2 H+ + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine. Source: EC:6.3.2.7, RHEA:17969
Comment
None
History
See term history for GO:0047482 at QuickGO
Chem. react.
has participant hydron
has participant UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate(4-)
has participant UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-gamma-glutamyl-L-lysinate(3-)
has participant L-lysinium(1+)
has participant hydrogenphosphate
has participant ADP(3-)
has participant ATP(4-)
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase activity (GO:0047482)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase activity [RO:0000057 relation] RO:0000057  hydron (CHEBI:15378)
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase activity [RO:0000057 relation] RO:0000057  UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate(4-) (CHEBI:83900)
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase activity [is_a relation] is_a  acid-amino acid ligase activity (GO:0016881)
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase activity [RO:0000057 relation] RO:0000057  UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-gamma-glutamyl-L-lysinate(3-) (CHEBI:83903)
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase activity [RO:0000057 relation] RO:0000057  L-lysinium(1+) (CHEBI:32551)
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase activity [RO:0000057 relation] RO:0000057  hydrogenphosphate (CHEBI:43474)
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase activity [RO:0000057 relation] RO:0000057  ADP(3-) (CHEBI:456216)
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase activity [RO:0000057 relation] RO:0000057  ATP(4-) (CHEBI:30616)

This term has no children.

EC
6.3.2.7
KEGG_REACTION
R02786
MetaCyc
6.3.2.7-RXN
RHEA
17969