AmiGO 2: Term Details for "3alpha,7alpha,12beta-trihydroxy-5beta-cholanate dehydrogenase activity" (GO:0047521)

Accession: GO:0047521
Name: 3alpha,7alpha,12beta-trihydroxy-5beta-cholanate dehydrogenase activity
Ontology: molecular_function
Synonyms: 12-beta-hydroxysteroid dehydrogenase activity, 12beta-hydroxy steroid (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity, 12beta-hydroxysteroid dehydrogenase activity, 12beta-hydroxysteroid:NADP+ 12-oxidoreductase activity
Alternate IDs: None
Definition: Catalysis of the reaction: 3alpha,7alpha,12beta-trihydroxy-5beta-cholanate + NADP+ = 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate + H+ + NADPH. Source: RHEA:21424, EC:1.1.1.238
Comment: None
History: See term history for GO:0047521 at QuickGO
Chem. react.: has participant NADPH(4-); has participant hydron; has participant 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate; has participant NADP(3-); has participant 3alpha,7alpha,12beta-trihydroxy-5beta-cholanate
Subset: None
Related: Link to all genes and gene products annotated to 3alpha,7alpha,12beta-trihydroxy-5beta-cholanate dehydrogenase activity (excluding "regulates").; Link to all direct and indirect annotations to 3alpha,7alpha,12beta-trihydroxy-5beta-cholanate dehydrogenase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for 3alpha,7alpha,12beta-trihydroxy-5beta-cholanate dehydrogenase activity (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

subject	relation	object
3alpha,7alpha,12beta-trihydroxy-5beta-cholanate dehydrogenase activity	is_a	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0033764)
3alpha,7alpha,12beta-trihydroxy-5beta-cholanate dehydrogenase activity	RO:0000057	NADPH(4-) (CHEBI:57783)
3alpha,7alpha,12beta-trihydroxy-5beta-cholanate dehydrogenase activity	RO:0000057	hydron (CHEBI:15378)
3alpha,7alpha,12beta-trihydroxy-5beta-cholanate dehydrogenase activity	RO:0000057	3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate (CHEBI:11901)
3alpha,7alpha,12beta-trihydroxy-5beta-cholanate dehydrogenase activity	RO:0000057	NADP(3-) (CHEBI:58349)
3alpha,7alpha,12beta-trihydroxy-5beta-cholanate dehydrogenase activity	RO:0000057	3alpha,7alpha,12beta-trihydroxy-5beta-cholanate (CHEBI:15755)

This term has no children.