AmiGO 2: Term Details for "cholestanetriol 26-monooxygenase activity" (GO:0047749)

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Term Information

Accession: GO:0047749
Name: cholestanetriol 26-monooxygenase activity
Ontology: molecular_function
Synonyms: 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 26-hydroxylase activity, 5beta-cholestane-3alpha,7alpha,12alpha-triol 26-hydroxylase activity, 5beta-cholestane-3alpha,7alpha,12alpha-triol hydroxylase activity, 5beta-cholestane-3alpha,7alpha,12alpha-triol,NADPH:oxygen oxidoreductase (26-hydroxylating), CYP27A, CYP27A1, cholestanetriol 26-hydroxylase activity, cholesterol 27-hydroxylase activity, sterol 27-hydroxylase activity, cytochrome P450 27A1' activity, 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol hydroxylase activity, sterol 26-hydroxylase activity
Alternate IDs: None
Definition: Catalysis of the reaction: 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol + NADPH + O2 = 5-beta-cholestane-3-alpha,7-alpha,12-alpha,26-tetraol + NADP+ + H2O. Source: MetaCyc:CHOLESTANETRIOL-26-MONOOXYGENASE-RXN, EC:1.14.15.15
Comment: None
History: See term history for GO:0047749 at QuickGO
Chem. react.: has participant di-mu-sulfido-diiron(2+); has participant 5beta-cholestane-3alpha,7alpha,12alpha-triol; has participant (25R)-5beta-cholestane-3alpha,7alpha,12alpha,26-tetrol; has participant hydron; has participant di-mu-sulfido-diiron(1+); has participant water; has participant dioxygen
Subset: None
Related: Link to all genes and gene products annotated to cholestanetriol 26-monooxygenase activity (excluding "regulates").; Link to all direct and indirect annotations to cholestanetriol 26-monooxygenase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for cholestanetriol 26-monooxygenase activity (excluding "regulates").

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For more information, please see the ontology relation documentation.

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Additional internal viewing options

GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016491 oxidoreductase activity
GO:0004497 monooxygenase activity
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
GO:0047749 cholestanetriol 26-monooxygenase activity

Parents of cholestanetriol 26-monooxygenase activity (GO:0047749)

subject	relation	object
cholestanetriol 26-monooxygenase activity	RO:0000057	di-mu-sulfido-diiron(2+) (CHEBI:33737)
cholestanetriol 26-monooxygenase activity	RO:0000057	5beta-cholestane-3alpha,7alpha,12alpha-triol (CHEBI:16496)
cholestanetriol 26-monooxygenase activity	RO:0000057	(25R)-5beta-cholestane-3alpha,7alpha,12alpha,26-tetrol (CHEBI:48939)
cholestanetriol 26-monooxygenase activity	RO:0000057	hydron (CHEBI:15378)
cholestanetriol 26-monooxygenase activity	RO:0000057	di-mu-sulfido-diiron(1+) (CHEBI:33738)
cholestanetriol 26-monooxygenase activity	RO:0000057	water (CHEBI:15377)
cholestanetriol 26-monooxygenase activity	RO:0000057	dioxygen (CHEBI:15379)
cholestanetriol 26-monooxygenase activity	is_a	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen (GO:0016709)

This term has no children.

EC: 1.14.15.15
MetaCyc: CHOLESTANETRIOL-26-MONOOXYGENASE-RXN
RHEA: 14373