Term Information

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Accession
GO:0047865
Name
dimethylglycine dehydrogenase activity
Ontology
molecular_function
Synonyms
N,N-dimethylglycine oxidase activity, N,N-dimethylglycine:(acceptor) oxidoreductase (demethylating), N,N-dimethylglycine:acceptor oxidoreductase (demethylating)
Alternate IDs
None
Definition
Catalysis of the reaction: N,N-dimethylglycine + electron-transfer flavoprotein + H2O = sarcosine + formaldehyde + reduced electron-transfer flavoprotein. Source: EC:1.5.8.4, RHEA:52856
Comment
Note that this was EC:1.5.99.2.
History
See term history for GO:0047865 at QuickGO
Chem. react.
has participant hydron
has participant FADH2(2-)
has participant (6S)-5,6,7,8-tetrahydrofolyl-poly(gamma-glutamate) macromolecule
has participant N,N-dimethylglycine zwitterion
has participant (6R)-5,10-methylenetetrahydrofolate poly(gamma-L-glutamate) macromolecule
has participant sarcosine zwitterion
has participant FAD(3-)
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of dimethylglycine dehydrogenase activity (GO:0047865)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
dimethylglycine dehydrogenase activity [RO:0000057 relation] RO:0000057  hydron (CHEBI:15378)
dimethylglycine dehydrogenase activity [RO:0000057 relation] RO:0000057  FADH2(2-) (CHEBI:58307)
dimethylglycine dehydrogenase activity [RO:0000057 relation] RO:0000057  (6S)-5,6,7,8-tetrahydrofolyl-poly(gamma-glutamate) macromolecule (CHEBI:141005)
dimethylglycine dehydrogenase activity [RO:0000057 relation] RO:0000057  N,N-dimethylglycine zwitterion (CHEBI:58251)
dimethylglycine dehydrogenase activity [RO:0000057 relation] RO:0000057  (6R)-5,10-methylenetetrahydrofolate poly(gamma-L-glutamate) macromolecule (CHEBI:136572)
dimethylglycine dehydrogenase activity [is_a relation] is_a  oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor (GO:0046997)
dimethylglycine dehydrogenase activity [RO:0000057 relation] RO:0000057  sarcosine zwitterion (CHEBI:57433)
dimethylglycine dehydrogenase activity [RO:0000057 relation] RO:0000057  FAD(3-) (CHEBI:57692)

This term has no children.

EC
1.5.8.4
KEGG_REACTION
R01565
MetaCyc
DIMETHYLGLYCINE-DEHYDROGENASE-RXN
Reactome
R-HSA-6797653
RHEA
52856