AmiGO 2: Term Details for "receptor ligand activity" (GO:0048018)

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Term Information

Accession: GO:0048018
Name: receptor ligand activity
Ontology: molecular_function
Synonyms: signaling molecule, signaling receptor ligand activity, vitamin D receptor activator activity, receptor agonist activity
Alternate IDs: GO:0071884
Definition: The activity of a gene product that interacts with a receptor to effect a change in the activity of the receptor. Ligands may be produced by the same, or different, cell that expresses the receptor. Ligands may diffuse extracellularly from their point of origin to the receiving cell, or remain attached to an adjacent cell surface (e.g. Notch ligands). Source: GOC:kv, GOC:pdt, GOC:molecular_function_refactoring
Comment: None
History: See term history for GO:0048018 at QuickGO
Chem. react.: None
Subset: goslim_chembl; goslim_drosophila; goslim_generic
Related: Link to all genes and gene products annotated to receptor ligand activity (excluding "regulates").; Link to all direct and indirect annotations to receptor ligand activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for receptor ligand activity (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

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Additional internal viewing options

GO:0008150 biological_process
GO:0065007 biological regulation
GO:0003674 molecular_function
GO:0005488 binding
GO:0009987 cellular process
GO:0098772 molecular function regulator activity
GO:0050789 regulation of biological process
GO:0050896 response to stimulus
GO:0007154 cell communication
GO:0051716 cellular response to stimulus
GO:0140677 molecular function activator activity
GO:0060089 molecular transducer activity
GO:0005515 protein binding
GO:0050794 regulation of cellular process
GO:0023052 signaling
GO:0030545 signaling receptor regulator activity
GO:0007165 signal transduction
GO:0030546 signaling receptor activator activity
GO:0038023 signaling receptor activity
GO:0005102 signaling receptor binding
GO:0048018 receptor ligand activity
GO:0042056 chemoattractant activity
GO:0045499 chemorepellent activity
GO:0005125 cytokine activity
GO:0038177 death receptor agonist activity
GO:0008083 growth factor activity
GO:0005179 hormone activity
GO:0016015 morphogen activity
GO:0160041 neuropeptide activity
GO:0001515 opioid peptide activity
GO:0140295 pathogen-derived receptor ligand activity
GO:0005186 pheromone activity

Parents of receptor ligand activity (GO:0048018)

subject	relation	object
receptor ligand activity	RO:0002213	signaling receptor activity (GO:0038023)
receptor ligand activity	is_a	signaling receptor binding (GO:0005102)
receptor ligand activity	BFO:0000050	signal transduction (GO:0007165)
receptor ligand activity	is_a	signaling receptor activator activity (GO:0030546)

Children of receptor ligand activity (GO:0048018)

subject	relation	object
receptor ligand inhibitor activity (GO:0141069)	RO:0002630	receptor ligand activity
morphogen activity (GO:0016015)	is_a	receptor ligand activity
chemoattractant activity (GO:0042056)	is_a	receptor ligand activity
opioid peptide activity (GO:0001515)	is_a	receptor ligand activity
death receptor agonist activity (GO:0038177)	is_a	receptor ligand activity
pathogen-derived receptor ligand activity (GO:0140295)	is_a	receptor ligand activity
hormone activity (GO:0005179)	is_a	receptor ligand activity
chemorepellent activity (GO:0045499)	is_a	receptor ligand activity
neuropeptide activity (GO:0160041)	is_a	receptor ligand activity
cytokine activity (GO:0005125)	is_a	receptor ligand activity
growth factor activity (GO:0008083)	is_a	receptor ligand activity
pheromone activity (GO:0005186)	is_a	receptor ligand activity

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