Term Information

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Accession
GO:0048240
Name
sperm capacitation
Ontology
biological_process
Synonyms
sperm activation
Alternate IDs
None
Definition
A process required for sperm to reach fertilization competence. Sperm undergo an incompletely understood series of morphological and molecular maturational processes, termed capacitation, involving, among other processes, protein tyrosine phosphorylation and increased intracellular calcium. Source: PMID:11820818, ISBN:978-3-642-58301-8, GOC:jid
Comment
Avian spermatozoa do not require a period of capacitation, since they are competent to fertilize the egg without a prolonged sojourn in the oviduct or in a capacitation medium in vitro. Therefore, sperm capacitation can only be applied to Aves to refer to gene products involved in processes that occur prior to sperm being deposited from the avian male. The term cannot apply to processes occurring in the avian female reproductive tract.
History
See term history for GO:0048240 at QuickGO
Chem. react.
None
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of sperm capacitation (GO:0048240)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
sperm capacitation [RO:0002162 relation] RO:0002162  Eukaryota (NCBITaxon:2759)
sperm capacitation [BFO:0000050 relation] BFO:0000050  spermatid development (GO:0007286)
sperm capacitation [is_a relation] is_a  developmental process involved in reproduction (GO:0003006)
sperm capacitation [is_a relation] is_a  cellular process involved in reproduction in multicellular organism (GO:0022412)
sperm capacitation [is_a relation] is_a  cell maturation (GO:0048469)
Children of sperm capacitation (GO:0048240)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
regulation of sperm capacitation (GO:1902490) [RO:0002211 relation] RO:0002211  sperm capacitation
positive regulation of sperm capacitation (GO:1902492) [RO:0002213 relation] RO:0002213  sperm capacitation
positive regulation of flagellated sperm motility involved in capacitation (GO:0060474) [BFO:0000050 relation] BFO:0000050  sperm capacitation
negative regulation of sperm capacitation (GO:1902491) [RO:0002212 relation] RO:0002212  sperm capacitation
seminal fluid (UBERON:0006530) [RO:0002216 relation] RO:0002216  sperm capacitation
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