AmiGO 2: Term Details for "isotype switching to IgE isotypes" (GO:0048289)

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Term Information

Accession: GO:0048289
Name: isotype switching to IgE isotypes
Ontology: biological_process
Synonyms: class switch recombination to IgE isotypes, class switching to IgE isotypes, isotype switch recombination to IgE isotypes
Alternate IDs: None
Definition: The switching of activated B cells from IgM biosynthesis to IgE biosynthesis, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and IgE constant region gene segments in the immunoglobulin heavy chain locus. Source: PMID:2113175, PMID:9186655, ISBN:0781735149, PMID:12370374
Comment: None
History: See term history for GO:0048289 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to isotype switching to IgE isotypes (excluding "regulates").; Link to all direct and indirect annotations to isotype switching to IgE isotypes (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for isotype switching to IgE isotypes (excluding "regulates").

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GO:0008150 biological_process
GO:0009987 cellular process
GO:0008152 metabolic process
GO:0071704 organic substance metabolic process
GO:0009058 biosynthetic process
GO:0044237 cellular metabolic process
GO:1901360 organic cyclic compound metabolic process
GO:0044238 primary metabolic process
GO:0048856 anatomical structure development
GO:0044249 cellular biosynthetic process
GO:0032502 developmental process
GO:0002252 immune effector process
GO:0006955 immune response
GO:0043170 macromolecule metabolic process
GO:0032501 multicellular organismal process
GO:0006139 nucleobase-containing compound metabolic process
GO:1901576 organic substance biosynthetic process
GO:0002250 adaptive immune response
GO:0002443 leukocyte mediated immunity
GO:0009059 macromolecule biosynthetic process
GO:0007275 multicellular organism development
GO:0090304 nucleic acid metabolic process
GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
GO:0006259 DNA metabolic process
GO:0010467 gene expression
GO:0002376 immune system process
GO:0002449 lymphocyte mediated immunity
GO:0050896 response to stimulus
GO:0048731 system development
GO:0019724 B cell mediated immunity
GO:0001775 cell activation
GO:0006310 DNA recombination
GO:0002520 immune system development
GO:0002440 production of molecular mediator of immune response
GO:0002263 cell activation involved in immune response
GO:0016064 immunoglobulin mediated immune response
GO:0002377 immunoglobulin production
GO:0045321 leukocyte activation
GO:0016444 somatic cell DNA recombination
GO:0002200 somatic diversification of immune receptors
GO:0002381 immunoglobulin production involved in immunoglobulin-mediated immune response
GO:0002366 leukocyte activation involved in immune response
GO:0046649 lymphocyte activation
GO:0002562 somatic diversification of immune receptors via germline recombination within a single locus
GO:0016445 somatic diversification of immunoglobulins
GO:0042113 B cell activation
GO:0002285 lymphocyte activation involved in immune response
GO:0002208 somatic diversification of immunoglobulins involved in immune response
GO:0016447 somatic recombination of immunoglobulin gene segments
GO:0002312 B cell activation involved in immune response
GO:0002204 somatic recombination of immunoglobulin genes involved in immune response
GO:0045190 isotype switching
GO:0048289 isotype switching to IgE isotypes
GO:0035708 interleukin-4-dependent isotype switching to IgE isotypes
GO:0048294 negative regulation of isotype switching to IgE isotypes
GO:0048295 positive regulation of isotype switching to IgE isotypes
GO:0048293 regulation of isotype switching to IgE isotypes

Parents of isotype switching to IgE isotypes (GO:0048289)

subject	relation	object
isotype switching to IgE isotypes	is_a	isotype switching (GO:0045190)

Children of isotype switching to IgE isotypes (GO:0048289)

subject	relation	object
regulation of isotype switching to IgE isotypes (GO:0048293)	RO:0002211	isotype switching to IgE isotypes
interleukin-4-dependent isotype switching to IgE isotypes (GO:0035708)	is_a	isotype switching to IgE isotypes
positive regulation of isotype switching to IgE isotypes (GO:0048295)	RO:0002213	isotype switching to IgE isotypes
negative regulation of isotype switching to IgE isotypes (GO:0048294)	RO:0002212	isotype switching to IgE isotypes

isotype switching to IgE isotypes