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prostaglandin-E2 9-reductase activity

Term Information

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Accession
GO:0050221
Name
prostaglandin-E2 9-reductase activity
Ontology
molecular_function
Synonyms
(5Z,13E)-(15S)-9alpha,11alpha,15-trihydroxyprosta-5,13-dienoate:NADP+ 9-oxidoreductase activity, 9-keto-prostaglandin E(2) reductase activity, 9-keto-prostaglandin E2 reductase activity, 9-ketoprostaglandin reductase activity, PGE(2) 9-ketoreductase activity, PGE(2) 9-oxoreductase activity, PGE-9-ketoreductase activity, PGE2 9-ketoreductase activity, PGE2 9-oxoreductase activity, PGE2-9-OR, PGE2-9-ketoreductase activity, prostaglandin E 9-ketoreductase activity, prostaglandin E2-9-oxoreductase activity, prostaglandin-E(2) 9-oxoreductase activity, prostaglandin-E2 9-oxoreductase activity, reductase, 15-hydroxy-9-oxoprostaglandin
Alternate IDs
None
Definition
Catalysis of the reaction: (5Z,13E)-(15S)-9-alpha,11-alpha,15-trihydroxyprosta-5,13-dienoate + NADP+ = (5Z,13E)-(15S)-11-alpha,15-dihydroxy-9-oxoprosta-5,13-dienoate + NADPH. Source: EC:1.1.1.189, MetaCyc:PROSTAGLANDIN-E2-9-REDUCTASE-RXN
Comment
None
History
See term history for GO:0050221 at QuickGO
Chem. react.
has participant NADPH(4-)
has participant hydron
has participant NADP(3-)
has participant prostaglandin E2(1-)
has participant prostaglandin F2alpha(1-)
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of prostaglandin-E2 9-reductase activity (GO:0050221)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
prostaglandin-E2 9-reductase activity [RO:0000057 relation] RO:0000057  NADPH(4-) (CHEBI:57783)
prostaglandin-E2 9-reductase activity [is_a relation] is_a  oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616)
prostaglandin-E2 9-reductase activity [RO:0000057 relation] RO:0000057  hydron (CHEBI:15378)
prostaglandin-E2 9-reductase activity [RO:0000057 relation] RO:0000057  NADP(3-) (CHEBI:58349)
prostaglandin-E2 9-reductase activity [RO:0000057 relation] RO:0000057  prostaglandin E2(1-) (CHEBI:606564)
prostaglandin-E2 9-reductase activity [RO:0000057 relation] RO:0000057  prostaglandin F2alpha(1-) (CHEBI:57404)

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