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Accession
GO:0050334
Name
thiaminase activity
Ontology
molecular_function
Synonyms
thiaminase II activity
Alternate IDs
None
Definition
Catalysis of the reaction: H2O + thiamine = 4-amino-5-hydroxymethyl-2-methylpyrimidine + 5-(2-hydroxyethyl)-4-methylthiazole + H+. Source: RHEA:17509, EC:3.5.99.2
Comment
None
History
See term history for GO:0050334 at QuickGO
Chem. react.
has participant thiamine(1+)
has participant water
has participant 4-amino-5-hydroxymethyl-2-methylpyrimidine
has participant 5-(2-hydroxyethyl)-4-methylthiazole
has participant hydron
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of thiaminase activity (GO:0050334)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
thiaminase activity [RO:0000057 relation] RO:0000057  thiamine(1+) (CHEBI:18385)
thiaminase activity [RO:0000057 relation] RO:0000057  water (CHEBI:15377)
thiaminase activity [RO:0000057 relation] RO:0000057  4-amino-5-hydroxymethyl-2-methylpyrimidine (CHEBI:16892)
thiaminase activity [RO:0000057 relation] RO:0000057  5-(2-hydroxyethyl)-4-methylthiazole (CHEBI:17957)
thiaminase activity [is_a relation] is_a  hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds (GO:0016810)
thiaminase activity [RO:0000057 relation] RO:0000057  hydron (CHEBI:15378)

This term has no children.

EC
3.5.99.2
KEGG_REACTION
R02133
MetaCyc
THIAMINASE-RXN
RHEA
17509