Term Information

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Accession
GO:0050440
Name
2-methylcitrate synthase activity
Ontology
molecular_function
Synonyms
2-methylcitrate oxaloacetate-lyase activity, MCS activity, methylcitrate synthase activity, methylcitrate synthetase activity, propanoyl-CoA:oxaloacetate C-propanoyltransferase (thioester-hydrolysing, 1-carboxyethyl-forming)
Alternate IDs
None
Definition
Catalysis of the reaction: H2O + oxaloacetate + propanoyl-CoA = (2R,3S)-2-methylcitrate + CoA + H+. Source: RHEA:23780
Comment
None
History
See term history for GO:0050440 at QuickGO
Chem. react.
has participant water
has participant coenzyme A(4-)
has participant propionyl-CoA(4-)
has participant oxaloacetate(2-)
has participant (2S,3S)-2-methylcitrate(3-)
has participant hydron
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of 2-methylcitrate synthase activity (GO:0050440)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
2-methylcitrate synthase activity [RO:0000057 relation] RO:0000057  water (CHEBI:15377)
2-methylcitrate synthase activity [is_a relation] is_a  acyltransferase activity, acyl groups converted into alkyl on transfer (GO:0046912)
2-methylcitrate synthase activity [RO:0000057 relation] RO:0000057  coenzyme A(4-) (CHEBI:57287)
2-methylcitrate synthase activity [RO:0000057 relation] RO:0000057  propionyl-CoA(4-) (CHEBI:57392)
2-methylcitrate synthase activity [RO:0000057 relation] RO:0000057  oxaloacetate(2-) (CHEBI:16452)
2-methylcitrate synthase activity [RO:0000057 relation] RO:0000057  (2S,3S)-2-methylcitrate(3-) (CHEBI:58853)
2-methylcitrate synthase activity [RO:0000057 relation] RO:0000057  hydron (CHEBI:15378)

This term has no children.

EC
2.3.3.5
KEGG_REACTION
R00931
MetaCyc
2-METHYLCITRATE-SYNTHASE-RXN
RHEA
23780