AmiGO 2: Term Details for "N-acetylneuraminate synthase activity" (GO:0050462)

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Term Information

Accession: GO:0050462
Name: N-acetylneuraminate synthase activity
Ontology: molecular_function
Synonyms: (NANA)condensing enzyme activity, N-acetylneuraminate pyruvate-lyase (pyruvate-phosphorylating) activity, N-acetylneuraminic acid synthase activity, NeuAc synthase activity, phosphoenolpyruvate:N-acetyl-D-mannosamine C-(1-carboxyvinyl)transferase (phosphate-hydrolysing, 2-carboxy-2-oxoethyl-forming)
Alternate IDs: None
Definition: Catalysis of the reaction: phosphoenolpyruvate + N-acetyl-D-mannosamine + H2O = phosphate + N-acetylneuraminate. Source: EC:2.5.1.56, MetaCyc:N-ACETYLNEURAMINATE-SYNTHASE-RXN
Comment: None
History: See term history for GO:0050462 at QuickGO
Chem. react.: has participant hydrogenphosphate; has participant phosphonatoenolpyruvate; has participant aldehydo-N-acetyl-D-mannosamine; has participant N-acetylneuraminate; has participant water
Subset: None
Related: Link to all genes and gene products annotated to N-acetylneuraminate synthase activity (excluding "regulates").; Link to all direct and indirect annotations to N-acetylneuraminate synthase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for N-acetylneuraminate synthase activity (excluding "regulates").

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GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016740 transferase activity
GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups
GO:0050462 N-acetylneuraminate synthase activity

Parents of N-acetylneuraminate synthase activity (GO:0050462)

subject	relation	object
N-acetylneuraminate synthase activity	RO:0000057	hydrogenphosphate (CHEBI:43474)
N-acetylneuraminate synthase activity	RO:0000057	phosphonatoenolpyruvate (CHEBI:58702)
N-acetylneuraminate synthase activity	RO:0000057	aldehydo-N-acetyl-D-mannosamine (CHEBI:17122)
N-acetylneuraminate synthase activity	is_a	transferase activity, transferring alkyl or aryl (other than methyl) groups (GO:0016765)
N-acetylneuraminate synthase activity	RO:0000057	N-acetylneuraminate (CHEBI:35418)
N-acetylneuraminate synthase activity	RO:0000057	water (CHEBI:15377)

This term has no children.

EC: 2.5.1.56
MetaCyc: N-ACETYLNEURAMINATE-SYNTHASE-RXN
RHEA: 19273