AmiGO 2: Term Details for "hyaluronan synthase activity" (GO:0050501)

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Term Information

Accession: GO:0050501
Name: hyaluronan synthase activity
Ontology: molecular_function
Synonyms: alternating UDP-alpha-N-acetyl-D-glucosamine:beta-D-glucuronosyl-(1,3)-[nascent hyaluronan] 4-N-acetyl-beta-D-glucosaminyltransferase and UDP-alpha-D-glucuronate:N-acetyl-beta-D-glucosaminyl-(1,4)-[nascent hyaluronan] 3-beta-D-glucuronosyltransferase activity, alternating UDP-alpha-N-acetyl-D-glucosamine:beta-D-glucuronosyl-(1->3)-[nascent hyaluronan] 4-N-acetyl-beta-D-glucosaminyltransferase and UDP-alpha-D-glucuronate:N-acetyl-beta-D-glucosaminyl-(1->4)-[nascent hyaluronan] 3-beta-D-glucuronosyltransferase activity, seHAS, spHAS, HAS activity
Alternate IDs: None
Definition: Catalysis of the reaction: UDP-D-glucuronate + UDP-N-acetyl-D-glucosamine = [beta-N-acetyl-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->3)](n) + 2n UDP. Source: EC:2.4.1.212, MetaCyc:2.4.1.212-RXN
Comment: None
History: See term history for GO:0050501 at QuickGO
Chem. react.: has participant UDP(3-); has participant N-acetyl-beta-D-glucosaminyl-(1->4)-[hyaluronate]; has participant hydron; has participant UDP-alpha-D-glucuronate(3-); has participant hyaluronate
Subset: None
Related: Link to all genes and gene products annotated to hyaluronan synthase activity (excluding "regulates").; Link to all direct and indirect annotations to hyaluronan synthase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for hyaluronan synthase activity (excluding "regulates").

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For more information, please see the ontology relation documentation.

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Additional internal viewing options

GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016740 transferase activity
GO:0016757 glycosyltransferase activity
GO:0016758 hexosyltransferase activity
GO:0008194 UDP-glycosyltransferase activity
GO:0050501 hyaluronan synthase activity

Parents of hyaluronan synthase activity (GO:0050501)

subject	relation	object
hyaluronan synthase activity	is_a	UDP-glycosyltransferase activity (GO:0008194)
hyaluronan synthase activity	is_a	hexosyltransferase activity (GO:0016758)
hyaluronan synthase activity	RO:0000057	UDP(3-) (CHEBI:58223)
hyaluronan synthase activity	RO:0000057	N-acetyl-beta-D-glucosaminyl-(1->4)-[hyaluronate] (CHEBI:132154)
hyaluronan synthase activity	RO:0000057	hydron (CHEBI:15378)
hyaluronan synthase activity	RO:0000057	UDP-alpha-D-glucuronate(3-) (CHEBI:58052)
hyaluronan synthase activity	RO:0000057	hyaluronate (CHEBI:132153)

This term has no children.

EC: 2.4.1.212
MetaCyc: 2.4.1.212-RXN
Reactome: R-HSA-2160851
RHEA: 12528