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Accession
GO:0050613
Name
delta14-sterol reductase activity
Ontology
molecular_function
Synonyms
C-14 sterol reductase activity, D14-sterol reductase activity, sterol C-14 reductase activity, 4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol:NADP+ delta14-oxidoreductase activity, sterol C14-reductase activity
Alternate IDs
GO:0000251
Definition
Catalysis of the reaction: NADP+ + 4,4-dimethyl-5-alpha-cholesta-8,24-dien-3-beta-ol = NADPH + H+ + 4,4-dimethyl-5-alpha-cholesta-8,14,24-trien-3-beta-ol. Source: EC:1.3.1.70
Comment
Note that zymosterol is cholesta-8,24-dien-3-ol.
History
See term history for GO:0050613 at QuickGO
Chem. react.
has participant 14-demethyllanosterol
has participant NADP(3-)
has participant 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol
has participant NADPH(4-)
has participant hydron
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of delta14-sterol reductase activity (GO:0050613)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
delta14-sterol reductase activity [is_a relation] is_a  oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor (GO:0016628)
delta14-sterol reductase activity [RO:0000057 relation] RO:0000057  14-demethyllanosterol (CHEBI:18364)
delta14-sterol reductase activity [RO:0000057 relation] RO:0000057  NADP(3-) (CHEBI:58349)
delta14-sterol reductase activity [RO:0000057 relation] RO:0000057  4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol (CHEBI:17813)
delta14-sterol reductase activity [RO:0000057 relation] RO:0000057  NADPH(4-) (CHEBI:57783)
delta14-sterol reductase activity [RO:0000057 relation] RO:0000057  hydron (CHEBI:15378)

This term has no children.

EC
1.3.1.70
MetaCyc
RXN66-14
Reactome
R-HSA-194674
R-HSA-194698
RHEA
18561